PURSUIT risk score: Difference between revisions
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=== Function === | === Function === | ||
<br /> | |||
* By using multivariate regression analysis, the investigators established seven risk predictors for death and myocardial infarction (MI) in patients with acute coronary syndromes. | |||
* Five of these risk factors were then combined into a scoring system: | |||
** Higher age | |||
** Sex | |||
** Worst Canadian Cardiovascular Society (CCS) class of angina | |||
** Signs of heart failure | |||
** ST-segment depression on the index ECG<br /> | |||
Revision as of 22:16, 11 February 2020
Definition and History
The PURSUIT (Platelet glycoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy) risk score was developed in a randomized clinical trial which recruited 9,461 patients and compared eptifibatide (Integrilin) to placebo in the management of Unstable Angina (UA) or Non-ST elevation Myocardial Infarction (NSTEMI).
Function
- By using multivariate regression analysis, the investigators established seven risk predictors for death and myocardial infarction (MI) in patients with acute coronary syndromes.
- Five of these risk factors were then combined into a scoring system:
- Higher age
- Sex
- Worst Canadian Cardiovascular Society (CCS) class of angina
- Signs of heart failure
- ST-segment depression on the index ECG