PURSUIT risk score: Difference between revisions
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** Signs of heart failure | ** Signs of heart failure | ||
** ST-segment depression on the index ECG | ** ST-segment depression on the index ECG | ||
*Each of these elements is scored accordingly, resulting in a score ranging 1 - 18.<br /> | *Each of these elements is scored accordingly, resulting in a score ranging 1 - 18. | ||
* | |||
{| class="wikitable" | |||
|+PURSUIT Risk Score | |||
!Elements | |||
!Entry | |||
!Score | |||
|- | |||
|Age | |||
| | |||
* 50 | |||
* 60 | |||
* 70 | |||
* 80 | |||
| | |||
* 8 | |||
* 9 | |||
* 11 | |||
* 12 | |||
|- | |||
|Sex | |||
| | |||
| | |||
|- | |||
|Worst CCS class past 6 weeks | |||
| | |||
| | |||
|- | |||
| colspan="1" rowspan="1" |Signs of heart failure | |||
| | |||
| | |||
|- | |||
|ST depression on ECG | |||
| | |||
| | |||
|} | |||
*<br /> | |||
Revision as of 22:40, 11 February 2020
Definition and History
The PURSUIT (Platelet glycoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy) risk score was developed in a randomized clinical trial which recruited 9,461 patients and compared eptifibatide (Integrilin) to placebo in the management of Unstable Angina (UA) or Non-ST elevation Myocardial Infarction (NSTEMI).
Function
- By using multivariate regression analysis, the investigators established seven risk predictors for death and myocardial infarction (MI) in patients with acute coronary syndromes.
- Five of these risk factors were then combined into a scoring system:
- Higher age
- Sex
- Worst Canadian Cardiovascular Society (CCS) class of angina
- Signs of heart failure
- ST-segment depression on the index ECG
- Each of these elements is scored accordingly, resulting in a score ranging 1 - 18.
| Elements | Entry | Score |
|---|---|---|
| Age |
|
|
| Sex | ||
| Worst CCS class past 6 weeks | ||
| Signs of heart failure | ||
| ST depression on ECG |