PURSUIT risk score: Difference between revisions
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!Score | !Score | ||
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!Age | |||
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* 50 | * 50 | ||
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* 12 | * 12 | ||
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!Sex | |||
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* Male | |||
* Female | |||
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* 1 | |||
* 0 | |||
|- | |- | ||
!Worst CCS class past 6 weeks | |||
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* No angina/CCS I/II | |||
* CCS III/IV | |||
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* 0 | |||
* 2 | |||
|- | |- | ||
! colspan="1" rowspan="1" |Signs of heart failure | |||
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* 2 | |||
|- | |- | ||
!ST depression on ECG | |||
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* 1 | |||
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*<br /> | *<br /> | ||
Revision as of 22:42, 11 February 2020
Definition and History
The PURSUIT (Platelet glycoprotein IIb/IIIa in Unstable angina: Receptor Suppression Using Integrilin Therapy) risk score was developed in a randomized clinical trial which recruited 9,461 patients and compared eptifibatide (Integrilin) to placebo in the management of Unstable Angina (UA) or Non-ST elevation Myocardial Infarction (NSTEMI).
Function
- By using multivariate regression analysis, the investigators established seven risk predictors for death and myocardial infarction (MI) in patients with acute coronary syndromes.
- Five of these risk factors were then combined into a scoring system:
- Higher age
- Sex
- Worst Canadian Cardiovascular Society (CCS) class of angina
- Signs of heart failure
- ST-segment depression on the index ECG
- Each of these elements is scored accordingly, resulting in a score ranging 1 - 18.
| Elements | Entry | Score |
|---|---|---|
| Age |
|
|
| Sex |
|
|
| Worst CCS class past 6 weeks |
|
|
| Signs of heart failure |
| |
| ST depression on ECG |
|