Myxoma classification: Difference between revisions
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* Based on the location and biological behavior of [[Symptom|symptoms]], cardiac myxomas may be classified into two groups: '''typical''' and '''atypical''' | * Based on the location and biological behavior of [[Symptom|symptoms]], cardiac myxomas may be classified into two groups: '''typical''' and '''atypical''' | ||
*'''Typical''' | *'''Typical''': | ||
**In typical cases, cardiac myxomas are almost always single, and there is a striking predilection for the left atrium, with approximately 75-86% occurring there.<ref name="pmid10903697">{{cite journal |vauthors=Grebenc ML, Rosado de Christenson ML, Burke AP, Green CE, Galvin JR |title=Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation |journal=Radiographics |volume=20 |issue=4 |pages=1073–103; quiz 1110–1, 1112 |year=2000 |pmid=10903697 |doi=10.1148/radiographics.20.4.g00jl081073 |url=}}</ref><ref name="pmid23460447">{{cite journal |vauthors=Amano J, Nakayama J, Yoshimura Y, Ikeda U |title=Clinical classification of cardiovascular tumors and tumor-like lesions, and its incidences |journal=Gen Thorac Cardiovasc Surg |volume=61 |issue=8 |pages=435–47 |year=2013 |pmid=23460447 |pmc=3732772 |doi=10.1007/s11748-013-0214-8 |url=}}</ref><ref name="pmid7446701">{{cite journal |vauthors=Wold LE, Lie JT |title=Cardiac myxomas: a clinicopathologic profile |journal=Am. J. Pathol. |volume=101 |issue=1 |pages=219–40 |year=1980 |pmid=7446701 |pmc=1903582 |doi= |url=}}</ref> | **In typical cases, cardiac myxomas are almost always single, and there is a striking predilection for the left atrium, with approximately 75-86% occurring there.<ref name="pmid10903697">{{cite journal |vauthors=Grebenc ML, Rosado de Christenson ML, Burke AP, Green CE, Galvin JR |title=Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation |journal=Radiographics |volume=20 |issue=4 |pages=1073–103; quiz 1110–1, 1112 |year=2000 |pmid=10903697 |doi=10.1148/radiographics.20.4.g00jl081073 |url=}}</ref><ref name="pmid23460447">{{cite journal |vauthors=Amano J, Nakayama J, Yoshimura Y, Ikeda U |title=Clinical classification of cardiovascular tumors and tumor-like lesions, and its incidences |journal=Gen Thorac Cardiovasc Surg |volume=61 |issue=8 |pages=435–47 |year=2013 |pmid=23460447 |pmc=3732772 |doi=10.1007/s11748-013-0214-8 |url=}}</ref><ref name="pmid7446701">{{cite journal |vauthors=Wold LE, Lie JT |title=Cardiac myxomas: a clinicopathologic profile |journal=Am. J. Pathol. |volume=101 |issue=1 |pages=219–40 |year=1980 |pmid=7446701 |pmc=1903582 |doi= |url=}}</ref> | ||
*'''atypical'''. | |||
**In atypical cases, presentation is usually early and multicentricity is more common. They are more frequently located on the right side of the heart (38%), or in the [[left ventricle]] (5%). There is also recurrence after [[surgical]] excision (12%–22%) and an association with other conditions, such as the [[Carney complex]].<ref name="pmid10903697" /> | **In atypical cases, presentation is usually early and multicentricity is more common. They are more frequently located on the right side of the heart (38%), or in the [[left ventricle]] (5%). There is also recurrence after [[surgical]] excision (12%–22%) and an association with other conditions, such as the [[Carney complex]].<ref name="pmid10903697" /> | ||
* Cardiac myxomas are anatomically distributed, as following:<ref name="pmid10903697" /> | * Cardiac myxomas are anatomically distributed, as following:<ref name="pmid10903697" /> | ||
Revision as of 19:52, 27 February 2020
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Myxoma classification On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sogand Goudarzi, MD [2] Maria Fernanda Villarreal, M.D. [3]
Overview
Cardiac myxomas are classified by the World Health Organization (WHO) histological classification of tumors of the heart, as "Benign tumors and tumor-like lesions" and categorized into a type of pluripotent mesenchymal tumor.
Classification
- Based on the location and biological behavior of symptoms, cardiac myxomas may be classified into two groups: typical and atypical
- Typical:
- atypical.
- In atypical cases, presentation is usually early and multicentricity is more common. They are more frequently located on the right side of the heart (38%), or in the left ventricle (5%). There is also recurrence after surgical excision (12%–22%) and an association with other conditions, such as the Carney complex.[1]
- Cardiac myxomas are anatomically distributed, as following:[1]
- Atria (95%)
- Left (75%)
- Right (20%)
- Ventricles (5%)
- Atria (95%)
- There is no established histological differentiation between both type of cardiac myxomas (typical and atypical).[4]
References
- ↑ 1.0 1.1 1.2 Grebenc ML, Rosado de Christenson ML, Burke AP, Green CE, Galvin JR (2000). "Primary cardiac and pericardial neoplasms: radiologic-pathologic correlation". Radiographics. 20 (4): 1073–103, quiz 1110–1, 1112. doi:10.1148/radiographics.20.4.g00jl081073. PMID 10903697.
- ↑ Amano J, Nakayama J, Yoshimura Y, Ikeda U (2013). "Clinical classification of cardiovascular tumors and tumor-like lesions, and its incidences". Gen Thorac Cardiovasc Surg. 61 (8): 435–47. doi:10.1007/s11748-013-0214-8. PMC 3732772. PMID 23460447.
- ↑ Wold LE, Lie JT (1980). "Cardiac myxomas: a clinicopathologic profile". Am. J. Pathol. 101 (1): 219–40. PMC 1903582. PMID 7446701.
- ↑ McCarthy PM, Piehler JM, Schaff HV, Pluth JR, Orszulak TA, Vidaillet HJ, Carney JA (1986). "The significance of multiple, recurrent, and "complex" cardiac myxomas". J. Thorac. Cardiovasc. Surg. 91 (3): 389–96. PMID 3951243.