COVID-19 classification: Difference between revisions
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==Overview== | ==Overview== | ||
SARS-CoV-2 viruses, the etiological agents of coronavirus disease 2019 (COVID-19), can be categorized into two major types, '''L''', the major type (~70%) and '''S''', the minor type (~30%). | SARS-CoV-2 [[Virus|viruses]], the [[Etiology|etiological]] agents of coronavirus disease 2019 (COVID-19), can be categorized into two major types, '''L''', the major type (~70%) and '''S''', the minor type (~30%). | ||
==Classification== | ==Classification== | ||
* SARS-CoV-2 viruses, the etiological agents of coronavirus disease 2019 (COVID-19), can be categorized into two major types:<ref name="LuCui20202">{{cite journal|last1=Lu|first1=Jian|last2=Cui|first2=Jie|last3=Qian|first3=Zhaohui|last4=Wang|first4=Yirong|last5=Zhang|first5=Hong|last6=Duan|first6=Yuange|last7=Wu|first7=Xinkai|last8=Yao|first8=Xinmin|last9=Song|first9=Yuhe|last10=Li|first10=Xiang|last11=Wu|first11=Changcheng|last12=Tang|first12=Xiaolu|title=On the origin and continuing evolution of SARS-CoV-2|journal=National Science Review|year=2020|issn=2095-5138|doi=10.1093/nsr/nwaa036}}</ref> | * SARS-CoV-2 [[Virus|viruses]], the [[Etiology|etiological]] agents of coronavirus disease 2019 (COVID-19), can be categorized into two major types:<ref name="LuCui20202">{{cite journal|last1=Lu|first1=Jian|last2=Cui|first2=Jie|last3=Qian|first3=Zhaohui|last4=Wang|first4=Yirong|last5=Zhang|first5=Hong|last6=Duan|first6=Yuange|last7=Wu|first7=Xinkai|last8=Yao|first8=Xinmin|last9=Song|first9=Yuhe|last10=Li|first10=Xiang|last11=Wu|first11=Changcheng|last12=Tang|first12=Xiaolu|title=On the origin and continuing evolution of SARS-CoV-2|journal=National Science Review|year=2020|issn=2095-5138|doi=10.1093/nsr/nwaa036}}</ref> | ||
**'''L''', the major type (~70%) | **'''L''', the major type (~70%) | ||
** '''S''', the minor type (~30%)<br /> | **'''S''', the minor type (~30%) | ||
=== Establishing the Classification === | |||
* One hundred and three SARS-CoV-2 virus strains were studied. | |||
* One hundred and one of them exhibited complete linkage between the two single nucleotide polymorphisms (SNPs): 72 strains exhibited a “CT” haplotype (defined as '''L''' type because T28,144 is in the codon of '''Leucine''') and 29 strains exhibited a “TC” haplotype (defined as '''S''' type because C28,144 is in the codon of '''Serine''') at these two sites.<br /> | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 19:56, 9 March 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]
Overview
SARS-CoV-2 viruses, the etiological agents of coronavirus disease 2019 (COVID-19), can be categorized into two major types, L, the major type (~70%) and S, the minor type (~30%).
Classification
- SARS-CoV-2 viruses, the etiological agents of coronavirus disease 2019 (COVID-19), can be categorized into two major types:[1]
- L, the major type (~70%)
- S, the minor type (~30%)
Establishing the Classification
- One hundred and three SARS-CoV-2 virus strains were studied.
- One hundred and one of them exhibited complete linkage between the two single nucleotide polymorphisms (SNPs): 72 strains exhibited a “CT” haplotype (defined as L type because T28,144 is in the codon of Leucine) and 29 strains exhibited a “TC” haplotype (defined as S type because C28,144 is in the codon of Serine) at these two sites.
References
- ↑ Lu, Jian; Cui, Jie; Qian, Zhaohui; Wang, Yirong; Zhang, Hong; Duan, Yuange; Wu, Xinkai; Yao, Xinmin; Song, Yuhe; Li, Xiang; Wu, Changcheng; Tang, Xiaolu (2020). "On the origin and continuing evolution of SARS-CoV-2". National Science Review. doi:10.1093/nsr/nwaa036. ISSN 2095-5138.