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Syncope, must be differentiated from other diseases that may cause, altered mental status, motor and or somatosensory deficits. The table below, summarizes the neurologic differential diagnosis for syncope:
{|
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diseases
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |History
! colspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Symptoms
! colspan="5" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Physical Examination
! colspan="3" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Diagnostic tests
! rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |Other Findings
|-
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Headache
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |↓ LOC
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Motor weakness
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Abnormal sensory
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Motor Deficit
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Sensory deficit
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Speech difficulty
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gait abnormality
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Cranial nerves
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |CT/MRI
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |CSF
! style="background: #4479BA; color: #FFFFFF; text-align: center;" |Gold standard test
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Subdural hematoma|Subdural hemorrhage]]<ref name="pmid216947552">{{cite journal| author=Birenbaum D, Bancroft LW, Felsberg GJ| title=Imaging in acute stroke. | journal=West J Emerg Med | year= 2011 | volume= 12 | issue= 1 | pages= 67-76 | pmid=21694755 | doi= | pmc=3088377 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21694755  }}</ref><ref name="pmid218073452">{{cite journal| author=DeLaPaz RL, Wippold FJ, Cornelius RS, Amin-Hanjani S, Angtuaco EJ, Broderick DF et al.| title=ACR Appropriateness Criteria® on cerebrovascular disease. | journal=J Am Coll Radiol | year= 2011 | volume= 8 | issue= 8 | pages= 532-8 | pmid=21807345 | doi=10.1016/j.jacr.2011.05.010 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21807345  }}</ref>
| align="left" style="background:#F5F5F5;" |
*[[Trauma]]
*Fall
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |[[Xanthochromia]]
| align="center" style="background:#F5F5F5;" |CT scan without contrast
| align="left" style="background:#F5F5F5;" |
*[[Confusion]]
*[[Dizziness]]
*[[Nausea and vomiting]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Neurosyphilis]]
| align="left" style="background:#F5F5F5;" |
*[[Sexually transmitted disease]]
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |↑ [[Leukocytes]] and [[protein]]
| align="center" style="background:#F5F5F5;" |Specific: CSF [[VDRL]]
Sensitive: CSF FTA-Ab
| align="left" style="background:#F5F5F5;" |
*[[Blindness]]
*[[Confusion]]
*[[Depression]]
*Abnormal [[gait]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Hypertensive encephalopathy]]
| align="left" style="background:#F5F5F5;" |
*[[Hypertension]]
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" |NA
| align="center" style="background:#F5F5F5;" |Clinical assesment
| align="left" style="background:#F5F5F5;" |
*[[Delirium]]
*Cortical [[blindness]]
*[[Cerebral edema]]
*[[Seizure]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Wernicke's encephalopathy|Wernicke’s encephalopathy]]
| align="left" style="background:#F5F5F5;" |
*History of alcohal abuse
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |NA
| align="center" style="background:#F5F5F5;" |Clinical assesment and lab findings
| align="left" style="background:#F5F5F5;" |
*[[Ophthalmoplegia]]
*[[Confusion]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Drug toxicity]]
| align="left" style="background:#F5F5F5;" |Medication history of


*[[Lithium]]
*[[Sedatives]]
*[[Phenytoin]]
*[[Carbamazepine]]
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |NA
| align="center" style="background:#F5F5F5;" |Drug screen test
| align="center" style="background:#F5F5F5;" |
* Confusion
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |Metabolic disturbances ([[electrolyte imbalance]], [[hypoglycemia]])
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |[[Hypoglycemia]], [[hyponatremia]], [[hypernatremia]], [[hypokalemia]], and [[hyperkalemia]]
| align="center" style="background:#F5F5F5;" |Depends on the cause
| align="left" style="background:#F5F5F5;" |
*[[Confusion]]
*[[Seizure]]
*[[Palpitation]]
*[[Sweating]]
*[[Dizziness]]
*[[Hypoglycemia]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Meningitis]] or [[encephalitis]]
| align="left" style="background:#F5F5F5;" |
*History of [[fever]] and [[malaise]]
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" | +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |↑ Leukocytes, ↑ protein, ↓ glucose
| align="center" style="background:#F5F5F5;" |[[CSF analysis]]
| align="left" style="background:#F5F5F5;" |
*[[Fever]]
*Neck rigidity
*[[Confusion]]
|-
! style="background: #DCDCDC; padding: 5px; text-align: center;" |[[Seizure]]
| align="left" style="background:#F5F5F5;" |
*Previous history of [[seizures]]
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |  +
| align="center" style="background:#F5F5F5;" |–
| align="center" style="background:#F5F5F5;" |Mass lesion
| align="center" style="background:#F5F5F5;" |Clinical assesment and [[EEG]]
| align="left" style="background:#F5F5F5;" |
*[[Confusion]]
*[[Apathy]]
*[[Irritability]]
|}
{| class="wikitable"
{| class="wikitable"
|+
|+

Revision as of 18:01, 28 April 2020


Common Causes of Sick sinus syndrome
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Images

Contrast enhanced CT: Aortic intramural hematoma, Courtesy of radiopaedia


Contrast enhanced CT: Aortic intramural hematoma, Courtesy of radiopaedia


Contrast enhanced CT: Aortic intramural hematoma, Courtesy of radiopaedia


Contrast enhanced CT: Aortic intramural hematoma, Courtesy of radiopaedia


Contrast enhanced CT: Aortic intramural hematoma, Courtesy of radiopaedia


Contrast enhanced CT: Aortic intramural hematoma, Courtesy of radiopaedia




Disease Name Age of Onset Gender Preponderance Signs/Symptoms Imaging Feature(s) Macroscopic Feature(s) Microscopic Feature(s) Laboratory Findings(s) Other Feature(s) ECG view