Sandbox:AyeshaFJ: Difference between revisions
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! colspan="2"|Criteria for the diagnosis of SLE | |||
|- | |||
| '''Clinical features''' | |||
| '''Characteristics''' | |||
|- | |||
|1)Malar rash | |||
|Fixed erythema, flat or raised, sparing the nasolabial folds | |||
|- | |||
|2)Discoid rash | |||
|Erythematous raised patches with adherent keratotic scarring and follicular plugging. | |||
|- | |||
|3)Photosensitivity | |||
|Rash due to unusual reaction to sunlight. | |||
|- | |||
|4)Oral ulcer | |||
|Oral or nasopharyngeal ulcers, which may be painless. | |||
|- | |||
|5)Arthritis | |||
|Non-erosive arthritis, involving <u>></u>2 peripheral joints. | |||
|- | |||
|6)Serositis | |||
|Pleuritis or pericarditis | |||
|- | |||
|7)Renal disorder | |||
|Persistent proteinura ( >0.5g/24hrs) or cellular casts (red cell, granular or tubular). | |||
|- | |||
|8)Neurological disorder | |||
|Seizure or psychosis, in the absence of provoking drugs or metabolic derangement. | |||
|- | |||
|9)Hematological disorder | |||
|Haemolytic anemia or leucopenia (<4 x10<sup>9</sup>) or lymphopenia (<1x10<sup>9</sup>) or thrombocytopenia (<100x10<sup>9</sup>) in the absence of offending drugs. | |||
|- | |||
|10)Immunological | |||
|Abnormal titre of Anti-DNA antibodies or presence of Sm antigen or positive antiphospholipid antibodies. | |||
|- | |||
|11)Anti-nuclear Antibody (ANA) | |||
|Abnormal ANA titre measured by immunofluorescence | |||
|- | |||
| rowspan="2"|Diagnosis of SLE is made in an adult if 4 out of 11 features are present either serially or simultaneously. | |||
| | |||
|} |
Revision as of 03:02, 9 May 2020
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief:
Criteria for the diagnosis of SLE | |
---|---|
Clinical features | Characteristics |
1)Malar rash | Fixed erythema, flat or raised, sparing the nasolabial folds |
2)Discoid rash | Erythematous raised patches with adherent keratotic scarring and follicular plugging. |
3)Photosensitivity | Rash due to unusual reaction to sunlight. |
4)Oral ulcer | Oral or nasopharyngeal ulcers, which may be painless. |
5)Arthritis | Non-erosive arthritis, involving >2 peripheral joints. |
6)Serositis | Pleuritis or pericarditis |
7)Renal disorder | Persistent proteinura ( >0.5g/24hrs) or cellular casts (red cell, granular or tubular). |
8)Neurological disorder | Seizure or psychosis, in the absence of provoking drugs or metabolic derangement. |
9)Hematological disorder | Haemolytic anemia or leucopenia (<4 x109) or lymphopenia (<1x109) or thrombocytopenia (<100x109) in the absence of offending drugs. |
10)Immunological | Abnormal titre of Anti-DNA antibodies or presence of Sm antigen or positive antiphospholipid antibodies. |
11)Anti-nuclear Antibody (ANA) | Abnormal ANA titre measured by immunofluorescence |
Diagnosis of SLE is made in an adult if 4 out of 11 features are present either serially or simultaneously. |