Menopause natural history, complications and prognosis

Natural History, Complications, and Prognosis

Natural History

• The symptoms of menopause typically develop in the menopausal transition years, that is define as perimenopause and start with amenorrhea for tow months and more in addition to vasomotor symptoms such as hot flashes, night sweats, palpitations, and migraines.This symptoms continued until reach to postmenopause, in this stage a woman has amenorrhea for on year and vasomotor symptoms in addition to other symptoms such as vaginal atrophy, decline in libido, stress incontinence and frequency, depression, sleep disturbance.
• If left untreated, [#]% of patients with [disease name] may progress to develop [manifestation 1], [manifestation 2], and [manifestation 3].

Complications

• Common complications of [disease name] include:
  • [Complication 1]
  • [Complication 2]
  • [Complication 3]

Prognosis

• Prognosis is generally excellent/good/poor, and the 1/5/10-year mortality/survival rate of patients with [disease name] is approximately [--]%.
• Depending on the extent of the [tumor/disease progression] at the time of diagnosis, the prognosis may vary. However, the prognosis is generally regarded as poor/good/excellent.
• The presence of [characteristic of disease] is associated with a particularly [good/poor] prognosis among patients with [disease/malignancy].
• [Subtype of disease/malignancy] is associated with the most favorable prognosis.
• The prognosis varies with the [characteristic] of tumor; [subtype of disease/malignancy] have the most favorable prognosis.