Asplenia primary prevention: Difference between revisions
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==Primary Prevention== | ==Primary Prevention== | ||
===Vaccination=== | |||
*Up to 87% of asplenic patients were found to have been infected with Streptococcus pneumoniae, one of the most common bacterial pathogen leading to infection in patients with asplenia.<ref name="pmid11253134">{{cite journal| author=Waghorn DJ| title=Overwhelming infection in asplenic patients: current best practice preventive measures are not being followed. | journal=J Clin Pathol | year= 2001 | volume= 54 | issue= 3 | pages= 214-8 | pmid=11253134 | doi=10.1136/jcp.54.3.214 | pmc=1731383 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11253134 }} </ref> | |||
*All patients with [[asplenia]] should receive the standard childhood and adolescent [[immunizations]] at the recommended age.<ref name="pmid24855431">{{cite journal| author=Salvadori MI, Price VE, Canadian Paediatric Society, Infectious Diseases and Immunization Committee| title=Preventing and treating infections in children with asplenia or hyposplenia. | journal=Paediatr Child Health | year= 2014 | volume= 19 | issue= 5 | pages= 271-8 | pmid=24855431 | doi= | pmc=4029242 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24855431 }} </ref> | |||
*Immunizations against [[Streptococcus pneumoniae]], [[Haemophilus influenzae type b]] (Hib), and [[Neisseria meningitidis]] should be ensured and may be administered on an earlier schedule than is routine, due to the risk of [[fulminant]] [[sepsis]] from [[encapsulated bacteria]]. | |||
**[[Pneumococcal vaccine]]: Both the conjugated 13-valent pneumococcal vaccine and the 23-valent polysaccharide vaccine is recommended for the asplenic patient. | |||
**[[Meningococcal vaccine]]: The conjugate quadrivalent meningococcal vaccine (MCV4) should be given. | |||
**[[Haemophilus influenzae type b]] (Hib): Children with [[asplenia]] should receive the Hib vaccine, who present with a life-threatening Hib [[infection]] because the [[infection]] itself does not confer [[lifelong]] protection. | |||
**[[Influenza vaccine]]: is recommended yearly, starting at six months of age, to lower the risk of [[secondary]] [[bacterial infections]]. | |||
**All asplenic patients may be at risk of [[Salmonella infection]] while travelling to less developed areas of the world and should be [[immunized]] for [[Salmonella typhi]]. | |||
*[ | **All [[age-appropriate]] [[vaccines]] and the yearly [[influenzae]] [[vaccine]] should be given to [[household]] contacts of [[asplenic patients]]. | ||
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==References== | ==References== |
Revision as of 10:42, 20 July 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anum Dilip, M.B.B.S[2]
Overview
There are no established measures for the primary prevention of [disease name].
OR
There are no available vaccines against [disease name].
OR
Effective measures for the primary prevention of [disease name] include [measure1], [measure2], and [measure3].
OR
[Vaccine name] vaccine is recommended for [patient population] to prevent [disease name]. Other primary prevention strategies include [strategy 1], [strategy 2], and [strategy 3].
Primary Prevention
Vaccination
- Up to 87% of asplenic patients were found to have been infected with Streptococcus pneumoniae, one of the most common bacterial pathogen leading to infection in patients with asplenia.[1]
- All patients with asplenia should receive the standard childhood and adolescent immunizations at the recommended age.[2]
- Immunizations against Streptococcus pneumoniae, Haemophilus influenzae type b (Hib), and Neisseria meningitidis should be ensured and may be administered on an earlier schedule than is routine, due to the risk of fulminant sepsis from encapsulated bacteria.
- Pneumococcal vaccine: Both the conjugated 13-valent pneumococcal vaccine and the 23-valent polysaccharide vaccine is recommended for the asplenic patient.
- Meningococcal vaccine: The conjugate quadrivalent meningococcal vaccine (MCV4) should be given.
- Haemophilus influenzae type b (Hib): Children with asplenia should receive the Hib vaccine, who present with a life-threatening Hib infection because the infection itself does not confer lifelong protection.
- Influenza vaccine: is recommended yearly, starting at six months of age, to lower the risk of secondary bacterial infections.
- All asplenic patients may be at risk of Salmonella infection while travelling to less developed areas of the world and should be immunized for Salmonella typhi.
- All age-appropriate vaccines and the yearly influenzae vaccine should be given to household contacts of asplenic patients.
References
- ↑ Waghorn DJ (2001). "Overwhelming infection in asplenic patients: current best practice preventive measures are not being followed". J Clin Pathol. 54 (3): 214–8. doi:10.1136/jcp.54.3.214. PMC 1731383. PMID 11253134.
- ↑ Salvadori MI, Price VE, Canadian Paediatric Society, Infectious Diseases and Immunization Committee (2014). "Preventing and treating infections in children with asplenia or hyposplenia". Paediatr Child Health. 19 (5): 271–8. PMC 4029242. PMID 24855431.