Narcolepsy historical perspective: Difference between revisions
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===Discovery=== | ===Discovery=== | ||
*The earliest account of narcolepsy was described by Thomas Willis (1621-1675) in [[patients]], "with a sleepy [[Dispositional Affect|disposition]] who suddenly [[falls]] fast asleep." | *The earliest account of narcolepsy was described by Thomas Willis (1621-1675) in [[patients]], "with a sleepy [[Dispositional Affect|disposition]] who suddenly [[falls]] fast asleep." | ||
*The term narcolepsy is derived by combining the Greek narke numbness, stupor and lepsis attack, to seize. | |||
*The first-ever convincing descriptions of narcolepsy and [[cataplexy]] were reported by Westphal (1877) and Fisher (1878) in Germany.<ref name="Fischer1878">{{cite journal|last1=Fischer|first1=Franz|title=Epileptoide Schlafzustände|journal=Archiv für Psychiatrie und Nervenkrankheiten|volume=8|issue=1|year=1878|pages=200–203|issn=0003-9373|doi=10.1007/BF01791317}}</ref> Both descriptions observed a [[hereditary]] factor in narcolepsy; the mother of Westphal's [[patient]] and a sister of Fisher's [[patient]] had similar [[clinical]] features. They also reported the unique [[Association (statistics)|association]] of excitement and [[sleepiness]] triggering episodes of [[muscle weakness]]. | *The first-ever convincing descriptions of narcolepsy and [[cataplexy]] were reported by Westphal (1877) and Fisher (1878) in Germany.<ref name="Fischer1878">{{cite journal|last1=Fischer|first1=Franz|title=Epileptoide Schlafzustände|journal=Archiv für Psychiatrie und Nervenkrankheiten|volume=8|issue=1|year=1878|pages=200–203|issn=0003-9373|doi=10.1007/BF01791317}}</ref> Both descriptions observed a [[hereditary]] factor in narcolepsy; the mother of Westphal's [[patient]] and a sister of Fisher's [[patient]] had similar [[clinical]] features. They also reported the unique [[Association (statistics)|association]] of excitement and [[sleepiness]] triggering episodes of [[muscle weakness]]. | ||
*French [[physician]] [[Jean-Baptiste-Édouard Gélineau]] (1880) described this [[condition]] in a wine merchant as [[neurosis]] or a functional [[condition]].<ref name="pmid17561602">{{cite journal| author=Schenck CH, Bassetti CL, Arnulf I, Mignot E| title=English translations of the first clinical reports on narcolepsy and cataplexy by Westphal and Gélineau in the late 19th century, with commentary. | journal=J Clin Sleep Med | year= 2007 | volume= 3 | issue= 3 | pages= 301-11 | pmid=17561602 | doi= | pmc=2564780 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17561602 }} </ref> He gave narcolepsy its name, which is the English form of the French word '''narcolepsie''', and also recognized this [[disorder]] as a specific [[clinical]] entity.<ref name="pmid9132972">{{cite journal| author=Janković S, Susić V, Sokić D, Lević Z| title=[Dr. John Baptiste Edouard Gélineau]. | journal=Srp Arh Celok Lek | year= 1996 | volume= 124 | issue= 11-12 | pages= 331-5 | pmid=9132972 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9132972 }} </ref> Although Gélineau named this [[Distinctive feature|distinct]] [[clinical]] entity he did not [[differentiate]] episodes of [[muscle weakness]] and [[sleep]] attacks triggered by [[emotions]] as he proposed common [[physiology]] for these two [[Distinctive feature|distinct]] [[symptoms]] of narcolepsy. | *French [[physician]] [[Jean-Baptiste-Édouard Gélineau]] (1880) described this [[condition]] in a wine merchant as [[neurosis]] or a functional [[condition]].<ref name="pmid17561602">{{cite journal| author=Schenck CH, Bassetti CL, Arnulf I, Mignot E| title=English translations of the first clinical reports on narcolepsy and cataplexy by Westphal and Gélineau in the late 19th century, with commentary. | journal=J Clin Sleep Med | year= 2007 | volume= 3 | issue= 3 | pages= 301-11 | pmid=17561602 | doi= | pmc=2564780 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17561602 }} </ref> He gave narcolepsy its name, which is the English form of the French word '''narcolepsie''', and also recognized this [[disorder]] as a specific [[clinical]] entity.<ref name="pmid9132972">{{cite journal| author=Janković S, Susić V, Sokić D, Lević Z| title=[Dr. John Baptiste Edouard Gélineau]. | journal=Srp Arh Celok Lek | year= 1996 | volume= 124 | issue= 11-12 | pages= 331-5 | pmid=9132972 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9132972 }} </ref> Although Gélineau named this [[Distinctive feature|distinct]] [[clinical]] entity he did not [[differentiate]] episodes of [[muscle weakness]] and [[sleep]] attacks triggered by [[emotions]] as he proposed common [[physiology]] for these two [[Distinctive feature|distinct]] [[symptoms]] of narcolepsy. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Muhammad Waleed Haider, M.D.[2]
Overview
Historical Perspective
Discovery
- The earliest account of narcolepsy was described by Thomas Willis (1621-1675) in patients, "with a sleepy disposition who suddenly falls fast asleep."
- The term narcolepsy is derived by combining the Greek narke numbness, stupor and lepsis attack, to seize.
- The first-ever convincing descriptions of narcolepsy and cataplexy were reported by Westphal (1877) and Fisher (1878) in Germany.[1] Both descriptions observed a hereditary factor in narcolepsy; the mother of Westphal's patient and a sister of Fisher's patient had similar clinical features. They also reported the unique association of excitement and sleepiness triggering episodes of muscle weakness.
- French physician Jean-Baptiste-Édouard Gélineau (1880) described this condition in a wine merchant as neurosis or a functional condition.[2] He gave narcolepsy its name, which is the English form of the French word narcolepsie, and also recognized this disorder as a specific clinical entity.[3] Although Gélineau named this distinct clinical entity he did not differentiate episodes of muscle weakness and sleep attacks triggered by emotions as he proposed common physiology for these two distinct symptoms of narcolepsy.
- The association between [important risk factor/cause] and [disease name] was made in/during [year/event].
- In [year], [scientist] was the first to discover the association between [risk factor] and the development of [disease name].
- In [year], [gene] mutations were first implicated in the pathogenesis of [disease name].
Landmark Events in the Development of Treatment Strategies
Impact on Cultural History
Famous Cases
The following are a few famous cases of [disease name]:
References
- ↑ Fischer, Franz (1878). "Epileptoide Schlafzustände". Archiv für Psychiatrie und Nervenkrankheiten. 8 (1): 200–203. doi:10.1007/BF01791317. ISSN 0003-9373.
- ↑ Schenck CH, Bassetti CL, Arnulf I, Mignot E (2007). "English translations of the first clinical reports on narcolepsy and cataplexy by Westphal and Gélineau in the late 19th century, with commentary". J Clin Sleep Med. 3 (3): 301–11. PMC 2564780. PMID 17561602.
- ↑ Janković S, Susić V, Sokić D, Lević Z (1996). "[Dr. John Baptiste Edouard Gélineau]". Srp Arh Celok Lek. 124 (11–12): 331–5. PMID 9132972.