Fatigue resident survival guide: Difference between revisions
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** [[chronic fatigue syndrome]] | ** [[chronic fatigue syndrome]] | ||
*[[Multiple sclerosis]] | *[[Multiple sclerosis]]<ref name="pmid28641771">{{cite journal| author=Akcali A, Zengin F, Aksoy SN, Zengin O| title=Fatigue in Multiple Sclerosis: Is it related to cytokines and hypothalamic-pituitary-adrenal axis? | journal=Mult Scler Relat Disord | year= 2017 | volume= 15 | issue= | pages= 37-41 | pmid=28641771 | doi=10.1016/j.msard.2017.03.004 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=28641771 }} </ref> | ||
*After malignancy treatment, patients can experience different patterns of fatigue from chemotherapy, radiation treatment, or surgery<ref name="pmid15014735">{{cite journal| author=Greenberg DB| title=Clinical Dimensions of Fatigue. | journal=Prim Care Companion J Clin Psychiatry | year= 2002 | volume= 4 | issue= 3 | pages= 90-93 | pmid=15014735 | doi=10.4088/pcc.v04n0301 | pmc=181235 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15014735 }} </ref>. | *After malignancy treatment, patients can experience different patterns of fatigue from chemotherapy, radiation treatment, or surgery<ref name="pmid15014735">{{cite journal| author=Greenberg DB| title=Clinical Dimensions of Fatigue. | journal=Prim Care Companion J Clin Psychiatry | year= 2002 | volume= 4 | issue= 3 | pages= 90-93 | pmid=15014735 | doi=10.4088/pcc.v04n0301 | pmc=181235 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=15014735 }} </ref>. | ||
Revision as of 10:40, 9 August 2020
Fatigue Resident Survival Guide |
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Overview |
Causes |
FIRE |
Diagnosis |
Treatment |
Do's |
Don'ts |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Mounika Lakhmalla, MBBS[2]Tayyaba Ali, M.D.[3]
Synonyms and keywords:: Weakness, Tiredness, Lethargy, Debility
Overview
Fatigue is a common nonspecific symptom due to a wide range of etiologies.Patients often use this term to describe a range of issues like difficulty initiating activity ; decreased capacity to maintain activity ; Trouble with concentration, memory, and emotional stability; or sleepiness or an uncontrollable need to sleep. The term fatigue can sometimes be used synonymously with Tiredness. Fatigue can present alone as a primary symptom or in association with other localizing symptoms.
Causes
Life Threatening Causes
Life-threatening causes include conditions that may result in death or permanent disability within 24 hours if left untreated.
Common Causes
- Infection
- Diabetes
- Hypercalcemia
- Anemia
- Rheumatologic diseases
- Inflammatory Bowel Disease[1]
- Neurologic injury
- Endocrine Causes:
- Hepatic-insufficiency
- Renal insufficiency
- Cardiopulmonary diseases
- Congestive heart failure
- Chronic obstructive pulmonary disease
- Peripheral vascular disease
- Atypical angina
- Obstructive sleep apnea.
- Myopathy
- Medications & Substance abuse
- Sedative-hypnotics
- Analgesics
- Antihypertensives
- Antidepressants
- Muscle relaxants
- Opioids
- Antibiotics
- Alcohol
- Marijuana
- Cocaine/other stimulants
- Anticancer agents (like cisplatin and Etoposide)
- Psychological Causes:
- Depression
- Anxiety
- Somatization disorder
- Dysthymic disorder
- chronic fatigue syndrome
- Multiple sclerosis[2]
- After malignancy treatment, patients can experience different patterns of fatigue from chemotherapy, radiation treatment, or surgery[3].
Diagnosis
The approach to diagnosis of fatigue is based on a step-wise testing strategy. Below is an algorithm summarising the identification and laboratory diagnosis of fatigue.
- Diagnostic evaluation of fatigue when it presents as a predominant symptom includes a detailed history and physical examination, basic laboratory studies, and updated cancer screening interventions.
- Additional diagnostic testing depends on associated localized findings.
- Extensive laboratory studies with out a suggestive history or physical exam findings is of limited diagnostic utility while evaluating chronic fatigue[4][5].
Seek proper history, ask patients to describe in their own words, what do they mean by fatigue? This will help distinguish fatigue from ❑ somnolence ❑ muscle weakness The history should also determine the characteristics, severity, and temporal pattern of fatigue: ❑ Onset – Abrupt or gradual, relationship to illness or life event ❑ Course – Stable, improving, or worsening ❑ Duration and daily pattern ❑ Factors that alleviate or exacerbate it ❑ Impact on daily life – Ability to work, socialize, participate in family activities ❑ Accommodations that the patient/family has had to make to deal with symptom | |||||||||||||||||||||||||||||||||||||||||||||||||||
Initial workup for Fatigue presenting with out other associated complaints. | |||||||||||||||||||||||||||||||||||||||||||||||||||
Initial workup for hemolysis: ❑ Indirect bilirubin ❑ serum haptoglobin ❑ Lactate dehydrogenase level ❑ Reticulocyte count ❑ Urinalysis | {{{ C02 }}} | {{{ C03 }}} | {{{ C04 }}} | {{{ C05 }}} | {{{ C06 }}} | ||||||||||||||||||||||||||||||||||||||||||||||
Treatment
Shown below is an algorithm summarizing the treatment of [[disease name]] according the the [...] guidelines.
Do's
- The content in this section is in bullet points.
Don'ts
- The content in this section is in bullet points.
References
- ↑ Grimstad T, Norheim KB (2016). "Fatigue in inflammatory bowel disease". Tidsskr Nor Laegeforen. 136 (20): 1721–1724. doi:10.4045/tidsskr.16.0134. PMID 27830906.
- ↑ Akcali A, Zengin F, Aksoy SN, Zengin O (2017). "Fatigue in Multiple Sclerosis: Is it related to cytokines and hypothalamic-pituitary-adrenal axis?". Mult Scler Relat Disord. 15: 37–41. doi:10.1016/j.msard.2017.03.004. PMID 28641771.
- ↑ Greenberg DB (2002). "Clinical Dimensions of Fatigue". Prim Care Companion J Clin Psychiatry. 4 (3): 90–93. doi:10.4088/pcc.v04n0301. PMC 181235. PMID 15014735.
- ↑ Ridsdale L, Evans A, Jerrett W, Mandalia S, Osler K, Vora H (1993). "Patients with fatigue in general practice: a prospective study". BMJ. 307 (6896): 103–6. doi:10.1136/bmj.307.6896.103. PMC 1693499. PMID 8343705.
- ↑ Lane TJ, Matthews DA, Manu P (1990). "The low yield of physical examinations and laboratory investigations of patients with chronic fatigue". Am J Med Sci. 299 (5): 313–8. doi:10.1097/00000441-199005000-00005. PMID 2337122.