Sandbox:Javaria: Difference between revisions
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<ref name="pmid22750769">{{cite journal |vauthors=Garg PK, Jain BK, Dubey IB, Sharma AK |title=Generalized lymphadenopathy: physical examination revisited |journal=Ann Saudi Med |volume=33 |issue=3 |pages=298–300 |date=2013 |pmid=22750769 |pmc=6078537 |doi=10.5144/0256-4947.2012.01.7.1525 |url=}}</ref><ref name="pmid24753638">{{cite journal |vauthors=Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A |title=Peripheral lymphadenopathy: approach and diagnostic tools |journal=Iran J Med Sci |volume=39 |issue=2 Suppl |pages=158–70 |date=March 2014 |pmid=24753638 |pmc=3993046 |doi= |url=}}</ref><ref name="pmid12484692">{{cite journal |vauthors=Bazemore AW, Smucker DR |title=Lymphadenopathy and malignancy |journal=Am Fam Physician |volume=66 |issue=11 |pages=2103–10 |date=December 2002 |pmid=12484692 |doi= |url=}}</ref> | |||
<ref name=" | {{familytree/start |summary=Management of lymphadenopathy}} | ||
{{familytree | | | | | | | | | | | | | | Z01 | | | | | | | |Z01='''History'''<div class="mw-collapsible mw-collapsed"><div style="float: left; text-align: left; width: 20em; padding:1em;"><br><div style="float: left; text-align: left; width: 20em; padding:1em;"> | |||
< | ❑[[Patient]] [[age]] (specific demographic characteristics ([[age]]) of certain [[malignancy|malignancies]])<br> | ||
❑ Duration of [[lymphadenopathy]] (<2 weeks or >1 year without an increase in size has low malignant potential)<br> | |||
{{familytree | | | | | | | | | | | | | | | ❑ Past medical history of underlying disease, suggestive of [[immunodeficiency]], or recurrent [[infections]]<br> | ||
❑ Sexual history suggestive of infection transmission<br> | |||
❑ Family history of certain malignant disorders ([[breast cancer]], or [[melanoma]])<br> | |||
❑ Exposure to communicable [[infectious disease]]s/ travel to high-risk areas<br> | |||
❑ Environmental exposure such as [[ultraviolet radiation|UV]] (skin cancer risk)/ animals/ occupational exposure <br> | |||
❑ Social history such as tobacco use, alcohol use (head and neck cancers risk)<br>}} | |||
{{familytree | | | | | | | | | | | | | | |!| | | | | | | }} | |||
{{familytree | | | | | | | | | | | | | | M01 | | | | | | | M01='''[[Physical exam]]'''<div class="mw-collapsible mw-collapsed"><div style="float: left; text-align: left; width: 20em; padding:1em;"><br>'''Appearance of the [[patient]]'''<br>[[Cachexia]] or surgical scar marks demonstrating previous malignancy treatment<br> | |||
[[Vital signs]]<br> | |||
*[[Temperature]]: High-grade / low-grade fever may demonstrate [[infection]]. <br> | |||
*[[Heart rate]]: [[Tachycardia]] with regular pulse may demonstrate [[infection]]. <br> | |||
*[[Respiratory rate]]: [[Tachypnea]] may demonstrate [[respiratory system]] involvement ([[infection]]\ [[metastasis]]).<br> | |||
*[[Blood pressure]]: [[Chronic hypertension]] or [[hypotension]] (may indicate [[sepsis]] as a complication).<br> | |||
*[[Oxygen saturation]]: may be low if the [[respiratory system]] is affected.}} | |||
{{familytree | | | | | | | | | | | | | | |!| | | | | | | }} | |||
{{familytree | | | | | | | | | | | | | |,|^|.| | | | | | |}} | {{familytree | | | | | | | | | | | | | |,|^|.| | | | | | |}} | ||
{{familytree | | | | | | | | | | | | Y01 | |Y02 | | | | | | |Y01=<div style="float: left; text-align: left; width: 20em; padding:1em;"> | {{familytree | | | | | | | | | | | | Y01 | |Y02 | | | | | | |Y01=<div style="float: left; text-align: left; width: 20em; padding:1em;">}} | ||
{{familytree | | | | | | | | | | | | |!| | |!| | | | | |}} | {{familytree | | | | | | | | | | | | |!| | |!| | | | | |}} | ||
{{familytree | | | | | | | | |,|-|-| K01 | |!| | | | | | |K01=<div style="float: left; text-align: left; width: 20em; padding:1em;"> | {{familytree | | | | | | | | |,|-|-| K01 | |!| | | | | | |K01=<div style="float: left; text-align: left; width: 20em; padding:1em;">}} | ||
{{familytree | | | | | | | | |!| | |!| | | |!| | | | | |}} | {{familytree | | | | | | | | |!| | |!| | | |!| | | | | |}} | ||
{{familytree | | | | | | | | X01 | |`|-|-|v|'| | | | | | |X01=<div style="float: left; text-align: left; width: 20em; padding:1em;">' | {{familytree | | | | | | | | X01 | |`|-|-|v|'| | | | | | |X01=<div style="float: left; text-align: left; width: 20em; padding:1em;">'❑ }} | ||
{{familytree | | | | | | | | |!| | | | | |!| | | | | | | |}} | {{familytree | | | | | | | | |!| | | | | |!| | | | | | | |}} | ||
{{familytree | | | | | | | | W01 | | | | |!| | | | | | | |W01=<div style="float: left; text-align: left; width: 20em; padding:1em;"> | {{familytree | | | | | | | | W01 | | | | |!| | | | | | | |W01=<div style="float: left; text-align: left; width: 20em; padding:1em;">}} | ||
{{familytree | | | | | | | | | | | | | | A01 | | | | | | | |A01=<div style="float: left; text-align: left; padding:1em;" | {{familytree | | | | | | | | | | | | | | A01 | | | | | | | |A01=<div style="float: left; text-align: left; padding:1em;">}} | ||
{{familytree | | | | | | | | | | |,|-|-|-|^|-|-|.| | | | }} | {{familytree | | | | | | | | | | |,|-|-|-|^|-|-|.| | | | }} | ||
{{familytree | | | | | | | | | | W01 | | | | | W02 | | | | | | |W01='''Patient is unstable''' <br> |W02='''Patient is stable'''}} | {{familytree | | | | | | | | | | W01 | | | | | W02 | | | | | | |W01='''Patient is unstable''' <br> |W02='''Patient is stable'''}} | ||
{{familytree | | | | | | | | | |!| | | | | | |!| | | | }} | {{familytree | | | | | | | | | |!| | | | | | |!| | | | }} | ||
{{familytree | | | | | | | | | L01 | | | | | |!| | | | L01=<div style="float: left; text-align: left; line-height: 150% " | {{familytree | | | | | | | | | L01 | | | | | |!| | | | L01=<div style="float: left; text-align: left; line-height: 150% ">}} | ||
{{familytree | | | | | | | | | | |`|-|-|-|v|-|'| | | | | }} | {{familytree | | | | | | | | | | |`|-|-|-|v|-|'| | | | | }} | ||
{{familytree | | | | | | | | | | | | | | |!| | | | | | | }} | {{familytree | | | | | | | | | | | | | | |!| | | | | | | }} | ||
{{familytree | | | | | | | | | | | | | | |!| | | | | | | }} | {{familytree | | | | | | | | | | | | | | |!| | | | | | | }} | ||
{{familytree | | | | | | | | | | | | | | E01 | | | | | | | | | |E01= | {{familytree | | | | | | | | | | | | | | E01 | | | | | | | | | |E01= }} | ||
{{familytree | | | | | | | | | | | | | | |!| | | | | | | | | |}} | {{familytree | | | | | | | | | | | | | | |!| | | | | | | | | |}} | ||
{{familytree | | | | | | | | | | | | | | Z02 | | | | | | | | |Z02=' | {{familytree | | | | | | | | | | | | | | Z02 | | | | | | | | |Z02='}} | ||
{{familytree | | | | | | |,|-|-|-|v|-|-|-|+|-|-|-|v|-|-|v|-|-|.| |}} | {{familytree | | | | | | |,|-|-|-|v|-|-|-|+|-|-|-|v|-|-|v|-|-|.| |}} | ||
{{familytree | | | | | | W01 | | W02 | | W03 | | W04 | | W05 | | W01= | {{familytree | | | | | | W01 | | W02 | | W03 | | W04 | | W05 | | W01= }} | ||
{{familytree | | | | | | |!| | | |!| | | |!| | | |!| | | |!| |!| | | | | |}} | {{familytree | | | | | | |!| | | |!| | | |!| | | |!| | | |!| |!| | | | | |}} | ||
{{familytree | | | | | | V01 | | V02 | | |!| | | V04 | | V05 |!| |V01= | {{familytree | | | | | | V01 | | V02 | | |!| | | V04 | | V05 |!| |V01=S}} | ||
{{familytree | | | | | | | | | | | | | | |!| | | | | | | | | |!| | | | | |}} | {{familytree | | | | | | | | | | | | | | |!| | | | | | | | | |!| | | | | |}} | ||
{{familytree | | | | | | | | | | | | | | A01 | | | | | | | | |!| | | | |A01= | {{familytree | | | | | | | | | | | | | | A01 | | | | | | | | |!| | | | |A01=}} | ||
{{familytree | | | | | | | | | | | | | | |!| | | | | | | | | |!| | | | | |}} | {{familytree | | | | | | | | | | | | | | |!| | | | | | | | | |!| | | | | |}} | ||
{{familytree | | | | | | | |,|-|-|-|-|-|-|^|-|-|-|-|-|-|.| | |!| | | }} | {{familytree | | | | | | | |,|-|-|-|-|-|-|^|-|-|-|-|-|-|.| | |!| | | }} | ||
{{familytree | | | | | | | C01 |-|-|-|.| | | | | | | | C03 |-|'| | | | | |C01 | {{familytree | | | | | | | C01 |-|-|-|.| | | | | | | | C03 |-|'| | | | | |C01}} | ||
{{familytree | | | | | | | |!| | | | |!| | | | | | | | |!| }} | {{familytree | | | | | | | |!| | | | |!| | | | | | | | |!| }} | ||
{{familytree | | | | | | | M01 | | | M02 | | | | | | | M03 | | M01= | {{familytree | | | | | | | M01 | | | M02 | | | | | | | M03 | | M01=}} | ||
{{familytree | | | | | | | |!| | | | |!| | | | | | | | |!| | | |}} | {{familytree | | | | | | | |!| | | | |!| | | | | | | | |!| | | |}} | ||
{{familytree | | | | | | | H01 | | | H02 | | | | |,|-|-|^|.| | | |H01= | {{familytree | | | | | | | H01 | | | H02 | | | | |,|-|-|^|.| | | |H01=}} | ||
{{familytree | | | | | | | | | | | | | | | | | | K01 | | | K02 | | | | K01= | {{familytree | | | | | | | | | | | | | | | | | | K01 | | | K02 | | | | K01=}} | ||
{{familytree | | | | | | | | | | | | | | | |,|-|-|^|.| | | |!| | | | |}} | {{familytree | | | | | | | | | | | | | | | |,|-|-|^|.| | | |!| | | | |}} | ||
{{familytree | | | | | | | | | | | | | | | |!| | | |!| | | J01 | | | | | |J01= | {{familytree | | | | | | | | | | | | | | | |!| | | |!| | | J01 | | | | | |J01=}} | ||
{{familytree | | | | | | | | | | | | | | | I01 | | I02 |-|'| | | |I01 | {{familytree | | | | | | | | | | | | | | | I01 | | I02 |-|'| | | |I01}} | ||
{{familytree/end}} | {{familytree/end}} | ||
[[ | |||
Do's | |||
[[Patients]] with [[immunodeficiency]] should have a wide differential diagnosis considering[[non-Hodgkin's lymphoma]] and [[Kaposi’s sarcoma]].<ref name="pmid12484692">{{cite journal |vauthors=Bazemore AW, Smucker DR |title=Lymphadenopathy and malignancy |journal=Am Fam Physician |volume=66 |issue=11 |pages=2103–10 |date=December 2002 |pmid=12484692 |doi= |url=}}</ref> | |||
Dont's | |||
*Physical examination should not be missed as a finding may change the course of differential diagnosis. Missing the physical exam may lead to unnecessary investigations and unnecessary delays.<ref name="pmid22750769">{{cite journal |vauthors=Garg PK, Jain BK, Dubey IB, Sharma AK |title=Generalized lymphadenopathy: physical examination revisited |journal=Ann Saudi Med |volume=33 |issue=3 |pages=298–300 |date=2013 |pmid=22750769 |pmc=6078537 |doi=10.5144/0256-4947.2012.01.7.1525 |url=}}</ref> | |||
*Fine-needle aspiration biopsy (FNAC) or excisional biopsy is the gold standard for tissue diagnosis and evaluation for LAD.<ref name="pmid24753638">{{cite journal |vauthors=Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A |title=Peripheral lymphadenopathy: approach and diagnostic tools |journal=Iran J Med Sci |volume=39 |issue=2 Suppl |pages=158–70 |date=March 2014 |pmid=24753638 |pmc=3993046 |doi= |url=}}</ref> |
Revision as of 22:30, 20 August 2020
History ❑Patient age (specific demographic characteristics (age) of certain malignancies) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Physical exam Appearance of the patient Cachexia or surgical scar marks demonstrating previous malignancy treatment
| |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
{{{Y02 }}} | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
'❑ | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Patient is unstable | Patient is stable | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
' | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
{{{ W02 }}} | {{{ W03 }}} | {{{ W04 }}} | {{{ W05 }}} | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
S | {{{ V02 }}} | {{{ V04 }}} | {{{ V05 }}} | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
{{{ C01 }}} | {{{ C03 }}} | {{{C01}}} | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
{{{ M02 }}} | {{{ M03 }}} | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
{{{ H02 }}} | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
{{{ K02 }}} | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
{{{ I01 }}} | {{{ I02 }}} | {{{I01}}} | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Do's
Patients with immunodeficiency should have a wide differential diagnosis consideringnon-Hodgkin's lymphoma and Kaposi’s sarcoma.[3]
Dont's
- Physical examination should not be missed as a finding may change the course of differential diagnosis. Missing the physical exam may lead to unnecessary investigations and unnecessary delays.[1]
- Fine-needle aspiration biopsy (FNAC) or excisional biopsy is the gold standard for tissue diagnosis and evaluation for LAD.[2]
- ↑ 1.0 1.1 Garg PK, Jain BK, Dubey IB, Sharma AK (2013). "Generalized lymphadenopathy: physical examination revisited". Ann Saudi Med. 33 (3): 298–300. doi:10.5144/0256-4947.2012.01.7.1525. PMC 6078537. PMID 22750769.
- ↑ 2.0 2.1 Mohseni S, Shojaiefard A, Khorgami Z, Alinejad S, Ghorbani A, Ghafouri A (March 2014). "Peripheral lymphadenopathy: approach and diagnostic tools". Iran J Med Sci. 39 (2 Suppl): 158–70. PMC 3993046. PMID 24753638.
- ↑ 3.0 3.1 Bazemore AW, Smucker DR (December 2002). "Lymphadenopathy and malignancy". Am Fam Physician. 66 (11): 2103–10. PMID 12484692.