Sandbox:Ifeoma Anaya: Difference between revisions

	Bowen's disease Microchapters
Overview
Historical Perspective
Pathophysiology
Causes
Epidemiology and Demographics
Natural History, Complications and Prognosis
Diagnosis
Treatment
Prevention
Differentiating Bowen's disease from other Diseases

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Revision as of 10:56, 1 September 2020

Synonyms and keywords: Exanthema subitum; sixth disease; roseola infantilis

Roseola Infantum

Overview

Historical Perspective

Previously known as "Roseola infantilis", the oldest known description of the disease dates as far back as 100 years ago by John Zahorsky, M.D in his publication in 1913 ^[1] ^[2]. Described as a symptom-complex of febrille erythema occuring in infants and not to be categorized alongside the erythema group of skin diseases. However, no clear-cut description was given to differentiate it from other pediatric skin eruptions. The name was subsequently dropped ^[1] .

Pathophysiology

Disease is caused by the Human Herpes Virus type 6 (HHV-6), children are the most commonly infected and more severe disease pathology can be seen in the immunocompromised because it remains latent in the body after primary infection ^[3] ^[4].

Causes

Epidemiology and Demographics

Natural History, Complications and Prognosis

Diagnosis

Treatment

Prevention

Differentiating Roseola Infantum from other Diseases


classification
SCC
BCC
Melanoma

Practice here

Mitosis in neuroendocrine tumor. Source: Wikimedia commons

**Classification of Waldenstrom macroglobulinemia (WM) and Related Disorders**
Criteria	Symptomatic WM	Asymptomatic WM	IgM-Related Disorders	MGUS
IgM monoclonal protein	+	+	+	+
Bone marrow infiltration	+	+	-	-
Symptoms attributable to IgM	+	-	+	-
Symptoms attributable to tumor infiltration	+	-	-	-

References

↑ ^1.0 ^1.1 Zahorsky, John (1913). "ROSEOLA INFANTUM". JAMA: The Journal of the American Medical Association. 61 (16): 1446. doi:10.1001/jama.1913.04350170028008. ISSN 0098-7484.
↑ Altschuler, Eric Lewin (2000). "OLDEST DESCRIPTION OF ROSEOLA AND IMPLICATIONS FOR THE ANTIQUITY OF HUMAN HERPESVIRUS 6". The Pediatric Infectious Disease Journal. 19 (9): 903. doi:10.1097/00006454-200009000-00025. ISSN 0891-3668.
↑ Bates M, Monze M, Bima H, Kapambwe M, Clark D, Kasolo FC; et al. (2009). "Predominant human herpesvirus 6 variant A infant infections in an HIV-1 endemic region of Sub-Saharan Africa". J Med Virol. 81 (5): 779–89. doi:10.1002/jmv.21455. PMID 19319952.
↑ Yoshikawa T (2001). "Human herpesvirus 6 infection in transplantation". Nagoya J Med Sci. 64 (1–2): 11–8. PMID 11486597.

[Zahorsky1913-1] 1.0 ^1.1 Zahorsky, John (1913). "ROSEOLA INFANTUM". JAMA: The Journal of the American Medical Association. 61 (16): 1446. doi:10.1001/jama.1913.04350170028008. ISSN 0098-7484.

[Altschuler2000-2] Altschuler, Eric Lewin (2000). "OLDEST DESCRIPTION OF ROSEOLA AND IMPLICATIONS FOR THE ANTIQUITY OF HUMAN HERPESVIRUS 6". The Pediatric Infectious Disease Journal. 19 (9): 903. doi:10.1097/00006454-200009000-00025. ISSN 0891-3668.

[pmid19319952-3] Bates M, Monze M, Bima H, Kapambwe M, Clark D, Kasolo FC; et al. (2009). "Predominant human herpesvirus 6 variant A infant infections in an HIV-1 endemic region of Sub-Saharan Africa". J Med Virol. 81 (5): 779–89. doi:10.1002/jmv.21455. PMID 19319952.

[pmid11486597-4] Yoshikawa T (2001). "Human herpesvirus 6 infection in transplantation". Nagoya J Med Sci. 64 (1–2): 11–8. PMID 11486597.

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[2]

[3]

[4]

@@ Line 5: / Line 5: @@
 Previously known as "Roseola infantilis", the oldest known description of the disease dates as far back as 100 years ago by John Zahorsky, M.D in his publication in 1913 <ref name="Zahorsky1913">{{cite journal|last1=Zahorsky|first1=John|title=ROSEOLA INFANTUM|journal=JAMA: The Journal of the American Medical Association|volume=61|issue=16|year=1913|pages=1446|issn=0098-7484|doi=10.1001/jama.1913.04350170028008}}</ref> <ref name="Altschuler2000">{{cite journal|last1=Altschuler|first1=Eric Lewin|title=OLDEST DESCRIPTION OF ROSEOLA AND IMPLICATIONS FOR THE ANTIQUITY OF HUMAN HERPESVIRUS 6|journal=The Pediatric Infectious Disease Journal|volume=19|issue=9|year=2000|pages=903|issn=0891-3668|doi=10.1097/00006454-200009000-00025}}</ref>. Described as a symptom-complex of febrille erythema occuring in infants and not to be categorized alongside the erythema group of skin diseases. However, no clear-cut description was given to differentiate it from other pediatric skin eruptions. The name was subsequently dropped <ref name="Zahorsky1913">{{cite journal|last1=Zahorsky|first1=John|title=ROSEOLA INFANTUM|journal=JAMA: The Journal of the American Medical Association|volume=61|issue=16|year=1913|pages=1446|issn=0098-7484|doi=10.1001/jama.1913.04350170028008}}</ref> .
 ==Pathophysiology==
+Disease is caused by the Human Herpes Virus type 6 (HHV-6), children are the most commonly infected and more severe disease pathology can be seen in the immunocompromised because it remains latent in the body after primary infection  <ref name="pmid19319952">{{cite journal| author=Bates M, Monze M, Bima H, Kapambwe M, Clark D, Kasolo FC | display-authors=etal| title=Predominant human herpesvirus 6 variant A infant infections in an HIV-1 endemic region of Sub-Saharan Africa. | journal=J Med Virol | year= 2009 | volume= 81 | issue= 5 | pages= 779-89 | pmid=19319952 | doi=10.1002/jmv.21455 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19319952  }} </ref> <ref name="pmid11486597">{{cite journal| author=Yoshikawa T| title=Human herpesvirus 6 infection in transplantation. | journal=Nagoya J Med Sci | year= 2001 | volume= 64 | issue= 1-2 | pages= 11-8 | pmid=11486597 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11486597  }} </ref>.
 ==Causes==
 ==Epidemiology and Demographics==