Traumatic brain injury laboratory findings: Difference between revisions
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{{Traumatic brain injury}} | {{Traumatic brain injury}} | ||
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==Overview== | ==Overview== | ||
An elevated concentration of CSF spectrin breakdown product (SBDP)120 and SBDP145, ubiquitin C-terminal hydrolase-L1 (UCH-L1), and glial fibrillary acidic protein (GFAP) is diagnostic of traumatic brain injury. | An elevated concentration of CSF spectrin breakdown product (SBDP)120 and SBDP145, ubiquitin C-terminal hydrolase-L1 (UCH-L1), and glial fibrillary acidic protein (GFAP) is diagnostic of traumatic brain injury. | ||
Revision as of 18:16, 1 September 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Joanna Ekabua, M.D. [2]
Overview
An elevated concentration of CSF spectrin breakdown product (SBDP)120 and SBDP145, ubiquitin C-terminal hydrolase-L1 (UCH-L1), and glial fibrillary acidic protein (GFAP) is diagnostic of traumatic brain injury.
Laboratory Findings
An elevated concentration of the following in CSF is diagnostic of traumatic brain injury.[1]
- Spectrin breakdown product (SBDP)120 and SBDP145
- Ubiquitin C-terminal hydrolase-L1 (UCH-L1)
- Glial fibrillary acidic protein (GFAP)
References
- ↑ Mondello S, Muller U, Jeromin A, Streeter J, Hayes RL, Wang KK (2011). "Blood-based diagnostics of traumatic brain injuries". Expert Rev Mol Diagn. 11 (1): 65–78. doi:10.1586/erm.10.104. PMC 3063529. PMID 21171922.