Relapsing fever medical therapy: Difference between revisions
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*[[Erythromycin]], [[Tetracyclines]], [[Chloramphenicol]], or [[Penicillins]] have all been shown to be effective for treating [[tick-borne relapsing fever]] [[Tick-borne relapsing fever|TBRF]]. Although the duration of therapy has not been well studied for TBRF, the current recommendation is seven days of [[antibiotic]] therapy. In contrast, [[louse-borne relapsing fever]] caused by [[Borrelia recurrentis|B. recurrentis]] can be treated with a single dose of [[antibiotics]]. | *[[Erythromycin]], [[Tetracyclines]], [[Chloramphenicol]], or [[Penicillins]] have all been shown to be effective for treating [[tick-borne relapsing fever]] [[Tick-borne relapsing fever|TBRF]]. Although the duration of therapy has not been well studied for TBRF, the current recommendation is seven days of [[antibiotic]] therapy. In contrast, [[louse-borne relapsing fever]] caused by [[Borrelia recurrentis|B. recurrentis]] can be treated with a single dose of [[antibiotics]]. | ||
*For young children and pregnant women either [[Erythromycin]] and/or [[Penicillin]] are recommended for the treatment of [[Tick-borne relapsing fever|TBRF]]. | *For young children and pregnant women either [[Erythromycin]] and/or [[Penicillin]] are recommended for the treatment of [[Tick-borne relapsing fever|TBRF]]. | ||
===Antimicrobial regimen=== | ===Antimicrobial regimen=== | ||
===Tick-Borne Relapsing Fever=== | ===Tick-Borne Relapsing Fever=== |
Revision as of 01:47, 25 September 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Maliha Shakil, M.D. [2]
Overview
Antimicrobial therapy for relapsing fever in adults depends on the vector (Tick-borne vs. Louse-borne) and includes either Doxycycline, Erythromycin, or Tetracyclines. Intravenous Ceftriaxone is added if either meningitis or encephalitis is present.
Medical Therapy
Antimicrobial Medications
- Erythromycin, Tetracyclines, Chloramphenicol, or Penicillins have all been shown to be effective for treating tick-borne relapsing fever TBRF. Although the duration of therapy has not been well studied for TBRF, the current recommendation is seven days of antibiotic therapy. In contrast, louse-borne relapsing fever caused by B. recurrentis can be treated with a single dose of antibiotics.
- For young children and pregnant women either Erythromycin and/or Penicillin are recommended for the treatment of TBRF.
Antimicrobial regimen
Tick-Borne Relapsing Fever
- Preferred regimen: Doxycycline 100 mg PO bid for 5-10 days[1]
- Alternative regimen: Erythromycin 500 mg PO qid for 5-10 days
- Note: If meningitis/encephalitis present, use Ceftriaxone 2 g IV q12h for 14 days
Louse-Borne Relapsing Fever
- Preferred regimen: Tetracycline 500 mg PO single dose
- Alternative regimen: Erythromycin 500 mg PO single dose
References
- ↑ Bartlett, John (2012). Johns Hopkins ABX guide : diagnosis and treatment of infectious diseases. Burlington, MA: Jones and Bartlett Learning. ISBN 978-1449625580.