Revefenacin

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Uma Maveli[2]

Adult Indications and Dosage

• The agreed dosage is 175 micrograms per day
  • Taken via a standard jet nebulizer (turns liquid medication into mist) connected to an air compressor
  • Makes it easy for patients with pulmonary problems

Adverse Reactions

Side Effects

• Headache
• Cough
• Problems regarding the upper respiratory system
• Back Pain

IV Compatibility

• Intravenous solution in healthy volunteers
  • Volume of distribution was 218 L
  • Intravenous solution radioactivity:
  • 54% came out as solid waste
  • 27% came out as liquid waste

Pharmacology

See Clinical Trials

Clinical Studies

Trials:

• Revefenacin proved to have long duration of action and low systemic exposure (doesn't affect the whole body) for patients struggling with Chronic Obstructive Pulmonary Disease or COPD
• 88 mcg of this drug can result in constructive bronchodilation (to helps patients breathe better)

How is it supplied

• Given to patients via jet nebulizer

Brand Names

• Yupelri