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| ==Causes== | | ==Causes== |
| Shortness in children and young adults nearly always results from below-average [[Human development (biology)|growth]] in childhood, while shortness in older adults usually results from loss of height due to [[kyphosis]] of the [[vertebral column|spine]] or collapsed [[vertebra]]e from [[osteoporosis]].
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| From a medical perspective, severe shortness can be a [[human variability|variation]] of normal, resulting from the interplay of multiple familial genes. It can also be due to one or more of many abnormal conditions, such as chronic (prolonged) [[hormone]] deficiency, [[malnutrition]], disease of a major organ system, mistreatment, treatment with certain drugs, [[chromosome|chromosomal]] deletions, [[genetic disease|inherited diseases]], [[birth defect]] [[syndrome]]s, bone structures fusing earlier than intended or many other causes.
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| HGH deficiency may occur at any time during infancy or childhood, with the most obvious sign being a noticeable slowing of growth. The deficiency may be genetic.
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| Increasing final height in children with short stature may be beneficial and could enhance HRQoL outcomes barring troublesome side effects and excessive cost of treatments.<ref name="urlHeight and Health-related Quality of Life">{{cite web |url=http://gghjournal.com/volume24/1/ab09.cfm |title=Height and Health-related Quality of Life |format= |work= |accessdate=}}</ref>
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| Disproportionate short stature
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| (Specific kind of Short stature) Shortcut to causes of Disproportionate short stature
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| Precocious puberty
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| (Specific kind of Short stature) Shortcut to causes of Precocious puberty
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| Proportionate short stature
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| (Specific kind of Short stature) Shortcut to causes of Proportionate short stature
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| Miscellaneous conditions
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| Malabsorption syndrome
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| Osteomalacia
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| Renal failure, chronic
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| Symptoms and signs
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| Hydrocephalus
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| Congenital conditions
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| Acrodermatitis enteropathica
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| Adiposogenital dystrophy
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| Beuren-Williams syndrome
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| Coffin syndrome 1
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| Combined pituitary hormone deficiency 5 (HESX1 gene)
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| Corpus callosum hypoplasia
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| Crome syndrome
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| Fallot tetralogy
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| Floating-Harbor syndrome
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| Hallermann-Streiff syndrome (HSS)
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| Hypothyroidism, congenital
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| Multiple pterygium syndrome
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| Nicolaides-Baraitser syndrome
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| Onat syndrome
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| Patent ductus arteriosus
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| Periodic hyperlysinemia
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| Russell-Silver dwarfism
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| Tricho-thiodystrophy
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| Xeroderma pigmentosum
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| Intrauterine acquired conditions
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| Intrauterine growth retardation
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| Chromosomal abnormalities
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| Brachydactyly-mental retardation syndrome
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| Chromosome 10q deletion syndrome
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| Chromosome 14 ring syndrome
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| Chromosome 15 ring syndrome
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| Chromosome 15q deletion syndrome
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| Chromosome 20 ring syndrome
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| Chromosome 4 ring syndrome
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| Chromosome 6 ring syndrome
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| Cri du chat syndrome 5p-
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| Deletion of short arm of chromosome 18
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| Down syndrome
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| Emanuel syndrome
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| Miller-Dieker syndrome
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| Prader-Willi syndrome
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| Smith-Magenis syndrome
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| Velocardiofacial syndrome
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| Wolf-Hirschhorn syndrome
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| XX male syndrome
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| Mendelian inherited conditions
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| Aspartylglucosaminuria
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| Bardet-Biedl syndrome
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| Beta thalassaemia (heterozygous)
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| Carbamoylphosphate synthetase deficiency
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| Complement 5 deficiency
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| Haemoglobin E disease
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| Hereditary sensorimotor neuropathy type 3
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| Kenny-Caffey-Linarelli syndrome
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| Leri-Weill dyschondrosteosis
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| Maple syrup urine disease
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| Nonbullous congenital ichthyosiform erythroderma
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| Say-Meyer syndrome
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| Sickle cell disease
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| Silver syndrome
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| Weill-Marchesani syndrome
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| Autosomal dominant conditions
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| 4-hydroxyphenylpyruvate hydroxylase deficiency
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| Branchio-oculo-facial syndrome
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| CHARGE syndrome
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| Cleidocranial dysplasia
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| C-like syndrome
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| Hischsprung disease-microcephaly-mental retardation syndrome
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| Kabuki make-up syndrome
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| Lenz-Majewski hyperostosis syndrome
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| Multiple lentigines syndrome
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| Neurofibromatosis-Noonan syndrome
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| Osteogenesis imperfecta
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| Pitt-Hopkins syndrome
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| Pseudohypoaldosteronism type 1, autosomal dominant
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| Pseudohypoparathyroidism type 1a
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| Pseudopseudohypoparathyroidism
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| Rubinstein-Taybi syndrome
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| Tarsal-carpal coalition syndrome
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| Trichorhinophalangeal syndrome type 3
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| Trismus pseudocamptodactyly syndrome
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| Velocardiofacial syndrome
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| Weismann-Netter-Stuhl syndrome
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| Autosomal recessive conditions
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| 3-Hydroxyisobutyric aciduria
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| 3M syndrome
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| Aase syndrome
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| Abetalipoproteinaemia
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| Adenylosuccinate lyase deficiency
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| Alpha-L-iduronidase deficiency (Hurler syndrome)
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| Aminomethyltransferase deficiency
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| Arginine:glycine amidinotransferase deficiency
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| Aspartoacylase deficiency
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| ATP6V0A2-related cutis laxa
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| Baller-Gerold syndrome
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| Bartter syndrome
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| Bloom syndrome
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| Bonnet-Dechaume-Blanc syndrome
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| Bowen-Conradi syndrome
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| C21-hydroxylase deficiency
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| Carbamoylphosphate synthetase deficiency
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| Carbohydrate deficient glycoprotein syndrome type 1a
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| Carbonic anhydrase type 2 deficiency
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| Carey-Fineman-Ziter syndrome
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| CCFDN syndrome
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| Cholesterol ester storage disease
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| Chylomicron retention disease
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| Cockayne syndrome
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| Craniomandibular dermatodysostosis
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| Cystic fibrosis
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| Cystinosis
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| De Barsy syndrome
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| Desmosterolosis
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| D-glycerate kinase deficiency
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| Dibasic aminoaciduria type 2
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| Donohue syndrome
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| Ellis-van Creveld syndrome
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| Faciocardiorenal syndrome
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| Fanconi anaemia
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| Fibrochondrogenesis
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| Filippi syndrome
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| Fucosidosis
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| Galactosamine-6-sulfatase deficiency
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| Galactose epimerase deficiency
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| Galactosialidosis
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| Gangliosidosis GM1, type 1
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| Gangliosidosis GM2, type 1
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| Gaucher disease
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| Geleophysic dysplasia
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| Geroderma osteodysplastica
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| Glycine decarboxylase deficiency
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| Glycogenosis type 1a
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| GRACILE syndrome
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| Hereditary orotic aciduria
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| Hereditary sensory and autonomic neuropathy type 3
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| Hurst microtia-absent patellae-micrognathia syndrome
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| Hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome
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| Hyperostosis corticalis deformans juvenilis
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| Intestinal enteropeptidase deficiency
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| Isobutyryl-CoA dehydrogenase deficiency
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| Jeune thoracic dystrophy syndrome
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| Johanson-Blizzard syndrome
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| Kartagener syndrome
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| Majeed syndrome
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| Marden-Walker syndrome
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| Martsolf syndrome
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| Metaphyseal chondrodysplasia, McKusick type
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| Methylmalonic acidemia and homocystinuria, cblC type
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| Mevalonate kinase deficiency
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| Microcephaly, primary autosomal recessive, type 1
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| Mitochondrial DNA depletion syndrome, hepatocerebral form
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| Mucolipidosis II alpha/beta
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| Mucolipidosis III alpha/beta
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| Mucolipidosis III gamma
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| Mucopolysaccharidosis IX
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| Mucopolysaccharidosis VII
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| Nephropathic early-onset cystinosis
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| Neuhauser syndrome
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| Niemann-Pick disease type B
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| Nijmegen chromosome breakage syndrome
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| Opitz trigonocephaly syndrome
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| Pitt-Rogers-Danks syndrome
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| Progressive familial intrahepatic cholestasis type 1
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| Pseudohypoaldosteronism type 1, autosomal recessive
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| Pyknodysostosis
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| Ramon syndrome
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| RAPADILINO syndrome
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| S-adenosylhomocysteine hydrolase deficiency
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| Sanjad-Sakati syndrome
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| Schwartz-Jampel-Aberfeld syndrome
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| Short chain acyl-CoA dehydrogenase deficiency
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| SHORT syndrome
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| Succinyl-CoA synthetase deficiency
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| Systemic hyalinosis
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| Tyrosinaemia type 1
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| Werner syndrome
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| Yunis-Varon syndrome
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| X-linked inherited conditions
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| Aarskog syndrome
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| Atkin-Flaitz-Patil syndrome
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| Barth syndrome
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| BRESHECK syndrome
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| Coffin-Lowry syndrome
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| Creatine deficiency syndrome, X-linked
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| Dwarfism-cerebral atrophy-keratosis follicularis syndrome
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| Gangliosidosis GM3
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| Glycerol kinase deficiency
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| Iduronate-2-sulfatase deficiency
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| Menkes disease
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| Microphthalmia-dermal aplasia-sclerocornea syndrome
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| Opitz-Kaveggia syndrome
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| Ornithine carbamyltransferase deficiency
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| Otopalatodigital syndrome type 2
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| Pelizaeus-Merzbacher disease
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| Renpenning syndrome 1
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| X-linked hypophosphataemia
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| X-linked mental retardation-hypotonic facies syndrome
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| Young-Hughes syndrome
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| Mitochondrial genome inherited conditions
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| MELAS
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| Nutritional conditions
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| Kwashiorkor
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| Malabsorption syndrome
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| Marasmus
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| Autoimmune conditions
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| Diabetes mellitus type 1
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| Inflammatory conditions
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| Celiac disease
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| Neoplastic conditions
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| Histiocytosis X
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| Obstetric conditions
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| Intrauterine growth retardation
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| Premature labour and/or delivery
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| Respiratory conditions
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| Bronchial asthma
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| Bronchiectasis
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| Trauma, mechanical and physical conditions
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| Child abuse
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| Choledochal cyst
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| Sexual abuse
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| Infection and infective conditions
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| Tonsillitis
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| Urinary tract infection
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| Helminths and helminthic conditions
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| Ascariasis
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| Bacteria and bacterial conditions
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| Mycobacterium tuberculosis
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| Drug groups
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| Cytotoxic therapeutic agents
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| Drugs, hormones and mediators
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| Prednisolone
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| [[Ciclesonide]]
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| ==Epidemiology and Demographics== | | ==Epidemiology and Demographics== |