Rhinosinusitis future or investigational therapies: Difference between revisions
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==Future or Investigational Therapies== | ==Future or Investigational Therapies== | ||
===Medical therapy=== | ===Medical therapy=== | ||
*Topical corticosteroids with improved delivery route: Recently, there has been efforts to investigate the efficacy of topical corticosteroids in treatment of chronic rhinosinusitis in order to minimizes | *Topical corticosteroids with improved delivery route: Recently, there has been efforts to investigate the efficacy of topical corticosteroids in treatment of chronic rhinosinusitis in order to increase the efficacy of the anti-inflammatory agents and minimizes the long term side effects of the systemic agents. Large volume delivery and steroid-eluting stents are recent successful approaches for direct delivery of steroids to the paranasal sinuses. However the cost effectiveness and possible need for stent replacement are limitations that should be considered. | ||
*Monoclonal antibodies against inflammatory agents: | *Monoclonal antibodies against inflammatory agents: | ||
*Identifying predictors of patient compliance and treatment response: | *Identifying predictors of patient compliance and treatment response: | ||
Revision as of 16:58, 4 December 2020
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Dima Nimri, M.D. [2]
Overview
Future or Investigational Therapies
Medical therapy
- Topical corticosteroids with improved delivery route: Recently, there has been efforts to investigate the efficacy of topical corticosteroids in treatment of chronic rhinosinusitis in order to increase the efficacy of the anti-inflammatory agents and minimizes the long term side effects of the systemic agents. Large volume delivery and steroid-eluting stents are recent successful approaches for direct delivery of steroids to the paranasal sinuses. However the cost effectiveness and possible need for stent replacement are limitations that should be considered.
- Monoclonal antibodies against inflammatory agents:
- Identifying predictors of patient compliance and treatment response:
- Alternative or complementary therapies for surgery in recurrent cases:
- Finding a "cure" for chronic rhinosinusitis: This could be possible by finding a method to correct the immune dysfunction in the patients.