Urticaria causes: Difference between revisions
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Disease name] may be caused by [cause1], [cause2], or [cause3]. | Disease name] may be caused by [cause1], [cause2], or [cause3]. | ||
==Causes== | ==Causes== | ||
===Common Causes=== | ===Common Causes=== | ||
Common causes of [[urticaria]] may include: | Common causes of [[urticaria]] may include:<ref name="pmid18713139">{{cite journal| author=Deacock SJ| title=An approach to the patient with urticaria. | journal=Clin Exp Immunol | year= 2008 | volume= 153 | issue= 2 | pages= 151-61 | pmid=18713139 | doi=10.1111/j.1365-2249.2008.03693.x | pmc=2492902 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18713139 }} </ref> | ||
*[[Idiopathic]] | *[[Idiopathic]] | ||
**Unknown [[etiology]] | **Unknown [[etiology]] | ||
*Immunological: | *[[immunology|Immunological]]: | ||
#Autoimmune IgG autoantibodies to IgE Receptor or IgE on mast cells is the responsible mechanism. | #[[Autoimmune]] [[Immunoglobulin G|IgG]] [[Autoantibody|autoantibodies]] to [[Immunoglobulin G|IgE]] Receptor or [[Immunoglobulin G|IgE]] on [[Mast cell|mast cells]] is the responsible mechanism. | ||
#IgE/contact: Contact with allergen cross-links specific IgE (SIgE) on mast cells. | #[[Immunoglobulin E|IgE]]/[[urticaria|contact urticaria]]: Contact with allergen cross-links specific [[Immunoglobulin E|IgE]] (SIgE) on mast cells. | ||
#Immune complex: | #[[Immune complex|Immune complex]]: | ||
##Mostly due to infections. | ##Mostly due to [[infection|infections]]. | ||
##Urticarial vasculitis | ##[[urticaria|Urticarial vasculitis]] | ||
*Non-immunological: | *Non-[[immunology|immunological]]: | ||
**Physical urticaria: Physical factors trigger histamine release from mast cells | **[[urticaria|Physical urticaria]]: Physical factors trigger [[histamine]] release from [[mast cell|mast cells]] | ||
**Drug treatment: | **[[medications|Drug treatment]]: | ||
***Sensitivity to Cyclo-oxygenase (COX)-inhibitors | ***Sensitivity to [[Cyclooxygenase|Cyclo-oxygenase]] ([[Cyclooxygenase|COX]])-inhibitors | ||
***Direct mast cell histamine release | ***Direct [[mast cell]] [[histamine]] release | ||
**Dietary pseudo-allergens: Sensitivity to natural salicylates, colourings, preservatives. | **[[Diet (nutrition)|Dietary]] pseudo-[[Allergen|allergens]]: Sensitivity to natural [[Salicylic acid|salicylates]], colourings, preservatives. | ||
**Medical conditions: | **[[Medicine|Medical conditions]]: | ||
***Urticaria pigmentosa: Increased mast cell load | ***[[urticaria|Urticaria pigmentosa]]: Increased [[mast cell]] load | ||
***Cryopyrin-associated | ***[[Cryopyrin-associated periodic syndrome|Periodic syndrome]] (CAPS): Due to a [[mutation]] in CIAS1 [[gene]]. | ||
Revision as of 18:00, 16 December 2020
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Anahita Deylamsalehi, M.D.[2]
Overview
Disease name] may be caused by [cause1], [cause2], or [cause3].
Causes
Common Causes
Common causes of urticaria may include:[1]
- Idiopathic
- Unknown etiology
- Immunological:
- Autoimmune IgG autoantibodies to IgE Receptor or IgE on mast cells is the responsible mechanism.
- IgE/contact urticaria: Contact with allergen cross-links specific IgE (SIgE) on mast cells.
- Immune complex:
- Mostly due to infections.
- Urticarial vasculitis
- Non-immunological:
- Physical urticaria: Physical factors trigger histamine release from mast cells
- Drug treatment:
- Sensitivity to Cyclo-oxygenase (COX)-inhibitors
- Direct mast cell histamine release
- Dietary pseudo-allergens: Sensitivity to natural salicylates, colourings, preservatives.
- Medical conditions:
- Urticaria pigmentosa: Increased mast cell load
- Periodic syndrome (CAPS): Due to a mutation in CIAS1 gene.
References
- ↑ Deacock SJ (2008). "An approach to the patient with urticaria". Clin Exp Immunol. 153 (2): 151–61. doi:10.1111/j.1365-2249.2008.03693.x. PMC 2492902. PMID 18713139.