Autoimmune lymphoproliferative syndrome historical perspective: Difference between revisions
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==Historical Perspective== | ==Historical Perspective== | ||
* | * [[Autoimmune]] [[Lymphoproliferative]] [[Syndrome]] was first discovered by Canale and Smith, in 1967.Five [[patients]] were reported with [[lymphadenopathy]], [[cytopenia]] and [[splenomegaly]]. | ||
*In [ | * The [[syndrome]] was initially named as Canale-Smith [[Syndrome]]. | ||
*In [ | * In 1992, a [[mutation]] of lpr([[lymphoproliferation]] [[phenotype]]) and gld(generalized [[lymphoproliferative]] [[disease]] [[phenotype]]), a [[human]] equivalent of [[murine]] [[disease]] is reported. | ||
*In 1995, association between inborn [[mutation]] of [[Fas]] [[gene]] and the [[development]] of [[Autoimmune]] [[lymphoproliferative]] [[syndrome]] was discovered. | |||
*In 2003, new [[mutation]] in [[Fas]] [[Ligand]] (FasL) [[gene mutation]] and [[caspase 8]] or 10 [[gene]] [[mutations]]. | |||
===Landmark Events in the Development of Treatment Strategies=== | ===Landmark Events in the Development of Treatment Strategies=== | ||
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===Famous Cases=== | ===Famous Cases=== | ||
The following are a few famous cases of [disease name]: | The following are a few famous cases of [disease name]: | ||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 20:04, 22 June 2021
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Autoimmune lymphoproliferative syndrome Microchapters |
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Differentiating Autoimmune lymphoproliferative syndrome from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Autoimmune lymphoproliferative syndrome historical perspective On the Web |
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American Roentgen Ray Society Images of Autoimmune lymphoproliferative syndrome historical perspective |
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FDA on Autoimmune lymphoproliferative syndrome historical perspective |
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CDC on Autoimmune lymphoproliferative syndrome historical perspective |
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Autoimmune lymphoproliferative syndrome historical perspective in the news |
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Blogs on Autoimmune lymphoproliferative syndrome historical perspective |
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Directions to Hospitals Treating Autoimmune lymphoproliferative syndrome |
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Risk calculators and risk factors for Autoimmune lymphoproliferative syndrome historical perspective |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Historical Perspective
- Autoimmune Lymphoproliferative Syndrome was first discovered by Canale and Smith, in 1967.Five patients were reported with lymphadenopathy, cytopenia and splenomegaly.
- The syndrome was initially named as Canale-Smith Syndrome.
- In 1992, a mutation of lpr(lymphoproliferation phenotype) and gld(generalized lymphoproliferative disease phenotype), a human equivalent of murine disease is reported.
- In 1995, association between inborn mutation of Fas gene and the development of Autoimmune lymphoproliferative syndrome was discovered.
- In 2003, new mutation in Fas Ligand (FasL) gene mutation and caspase 8 or 10 gene mutations.
Landmark Events in the Development of Treatment Strategies
Impact on Cultural History
Famous Cases
The following are a few famous cases of [disease name]: