Autoimmune lymphoproliferative syndrome epidemiology and demographics: Difference between revisions
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*[ | * [[Males]] are more commonly affected by [[Autoimmune lymphoproliferative syndrome]] than [[females]]. The [[male]] to [[female]] ratio is 14:4.<ref name="PriceShaw2014">{{cite journal|last1=Price|first1=Susan|last2=Shaw|first2=Pamela A.|last3=Seitz|first3=Amy|last4=Joshi|first4=Gyan|last5=Davis|first5=Joie|last6=Niemela|first6=Julie E.|last7=Perkins|first7=Katie|last8=Hornung|first8=Ronald L.|last9=Folio|first9=Les|last10=Rosenberg|first10=Philip S.|last11=Puck|first11=Jennifer M.|last12=Hsu|first12=Amy P.|last13=Lo|first13=Bernice|last14=Pittaluga|first14=Stefania|last15=Jaffe|first15=Elaine S.|last16=Fleisher|first16=Thomas A.|last17=Rao|first17=V. Koneti|last18=Lenardo|first18=Michael J.|title=Natural history of autoimmune lymphoproliferative syndrome associated with FAS gene mutations|journal=Blood|volume=123|issue=13|year=2014|pages=1989–1999|issn=0006-4971|doi=10.1182/blood-2013-10-535393}}</ref> | ||
===Region=== | ===Region=== | ||
Revision as of 02:49, 25 June 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Epidemiology and Demographics
Incidence
- The incidence of Autoimmune lymphoproliferative syndrome(ALPS) is unknown as many cases remain undiagnosed or misdiagnosed.[1]
Prevalence
- The prevalence is not known as many cases are left unidentified. So far 500 patients with ALPS have been identified coming from more than 300 families.[2]
Case-fatality rate/Mortality rate
- Mortality rate is 15% in patients with ALPS-FAS by age 50.[2]
Age
- Patients of all age groups may develop Autoimmune lymphoproliferative syndrome.[3]
- Typically ALPS appear in early childhood. The median age at diagnosis is 18 years.
Race
- There is no racial predilection to Autoimmune Lymphoproliferative Syndrome.
Gender
- Males are more commonly affected by Autoimmune lymphoproliferative syndrome than females. The male to female ratio is 14:4.[3]
Region
- The majority of [disease name] cases are reported in [geographical region].
- [Disease name] is a common/rare disease that tends to affect [patient population 1] and [patient population 2].
Developed Countries
Developing Countries
References
- ↑ Rao, V. Koneti; Oliveira, João Bosco (2011). "How I treat autoimmune lymphoproliferative syndrome". Blood. 118 (22): 5741–5751. doi:10.1182/blood-2011-07-325217. ISSN 0006-4971.
- ↑ 2.0 2.1 Shah, Shaili; Wu, Eveline; Rao, V. Koneti; Tarrant, Teresa K. (2014). "Autoimmune Lymphoproliferative Syndrome: an Update and Review of the Literature". Current Allergy and Asthma Reports. 14 (9). doi:10.1007/s11882-014-0462-4. ISSN 1529-7322.
- ↑ 3.0 3.1 Price, Susan; Shaw, Pamela A.; Seitz, Amy; Joshi, Gyan; Davis, Joie; Niemela, Julie E.; Perkins, Katie; Hornung, Ronald L.; Folio, Les; Rosenberg, Philip S.; Puck, Jennifer M.; Hsu, Amy P.; Lo, Bernice; Pittaluga, Stefania; Jaffe, Elaine S.; Fleisher, Thomas A.; Rao, V. Koneti; Lenardo, Michael J. (2014). "Natural history of autoimmune lymphoproliferative syndrome associated with FAS gene mutations". Blood. 123 (13): 1989–1999. doi:10.1182/blood-2013-10-535393. ISSN 0006-4971.