Angiodysplasia differential diagnosis: Difference between revisions
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Angiodysplasia must be differentiated from diverticulitis, hemorrhoids, colon cancer, massive upper GI bleed and inflammatory bowel disease. | Angiodysplasia must be differentiated from diverticulitis, hemorrhoids, colon cancer, massive upper GI bleed and inflammatory bowel disease. | ||
{| class="sortable mw-collapsible | {| class="sortable mw-collapsible" | ||
|- style="background: #4479BA; color: #FFFFFF; text-align: center;" | |- style="background: #4479BA; color: #FFFFFF; text-align: center;" | ||
! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |<small>Diseases</small> | ! rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |<small>Diseases</small> | ||
| colspan="6" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" | | | colspan="6" rowspan="1" style="background: #4479BA; color: #FFFFFF; text-align: center;" |<small>Clinical manifestations</small> | ||
! colspan="7" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |<small>Para-clinical findings</small> | ! colspan="7" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |<small>Para-clinical findings</small> | ||
| colspan="1" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" | | | colspan="1" rowspan="4" style="background: #4479BA; color: #FFFFFF; text-align: center;" |<small>Gold standard</small> | ||
|- | |- | ||
| colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" | | | colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |<small>Symptoms</small> | ||
! colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |<small>Physical examination</small> | ! colspan="3" rowspan="2" style="background: #4479BA; color: #FFFFFF; text-align: center;" |<small>Physical examination</small> | ||
|- | |- | ||
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| style="background: #F5F5F5; padding: 5px;" |<small>MRI abdomen</small> | | style="background: #F5F5F5; padding: 5px;" |<small>MRI abdomen</small> | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" |Colonoscopy after resolution of inflammation | | style="background: #F5F5F5; padding: 5px;" |<small>Colonoscopy after resolution of inflammation</small> | ||
|- | |- | ||
| style="background: #DCDCDC; padding: 5px; text-align: center;" |<small>Hemorrhoids</small> | | style="background: #DCDCDC; padding: 5px; text-align: center;" |<small>Hemorrhoids</small> | ||
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| style="background: #F5F5F5; padding: 5px;" |<small>Anal pain</small> | | style="background: #F5F5F5; padding: 5px;" |<small>Anal pain</small> | ||
| style="background: #F5F5F5; padding: 5px;" |<small>Anal protrusion</small> | | style="background: #F5F5F5; padding: 5px;" |<small>Anal protrusion</small> | ||
| style="background: #F5F5F5; padding: 5px;" |<small>Skin tags</small> | |||
| style="background: #F5F5F5; padding: 5px;" |<small>Fistulas or fissures</small> | |||
| style="background: #F5F5F5; padding: 5px;" |<small>Prolapsed hemorrhoid</small> | |||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
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| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |<small>External hemorrhoids - distal to dentate line.</small> | ||
<small>Internal hemorrhoids - proximal to dentate line.</small> | |||
| style="background: #F5F5F5; padding: 5px;" |<small>Anoscopy</small> | | style="background: #F5F5F5; padding: 5px;" |<small>Anoscopy</small> | ||
|- | |- | ||
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| style="background: #F5F5F5; padding: 5px;" |<small>Bowel habits change</small> | | style="background: #F5F5F5; padding: 5px;" |<small>Bowel habits change</small> | ||
| style="background: #F5F5F5; padding: 5px;" |<small>Weight loss</small> | | style="background: #F5F5F5; padding: 5px;" |<small>Weight loss</small> | ||
| style="background: #F5F5F5; padding: 5px;" |<small>Lmyphadenopathies</small> | |||
| style="background: #F5F5F5; padding: 5px;" |<small>Abdominal mass</small> | |||
| style="background: #F5F5F5; padding: 5px;" |<small>Hepatomegaly (metastasis)</small> | |||
| style="background: #F5F5F5; padding: 5px;" |<small>Tumor marker - CEA</small> | |||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" |<small>CT with contrast chest, abdomen and pelvis</small> | |||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Majority of colorectal cancers are carcinomas. | ||
| style="background: #F5F5F5; padding: 5px;" |<small>Colonoscopy</small> | | style="background: #F5F5F5; padding: 5px;" |<small>Colonoscopy</small> | ||
|- | |- | ||
| style="background: #DCDCDC; padding: 5px; text-align: center;" |<small>Massive upper GI bleed</small> | | style="background: #DCDCDC; padding: 5px; text-align: center;" |<small>Massive upper GI bleed</small> | ||
| style="background: #F5F5F5; padding: 5px;" |Hematemesis | |||
| style="background: #F5F5F5; padding: 5px;" |Abdominal pain | |||
| style="background: #F5F5F5; padding: 5px;" |Melena | |||
| style="background: #F5F5F5; padding: 5px;" |Hemodynamic instability | |||
| style="background: #F5F5F5; padding: 5px;" |Upper abdominal tenderness | |||
| style="background: #F5F5F5; padding: 5px;" |Pale skin | |||
| style="background: #F5F5F5; padding: 5px;" |Acute bleeding - normocytic anemia | |||
| style="background: #F5F5F5; padding: 5px;" |Elevated BUN-to-Creatinine ratio >30:1 | |||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" |CT angiography | |||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" | | ||
| style="background: #F5F5F5; padding: 5px;" | | | style="background: #F5F5F5; padding: 5px;" |Endoscopy | ||
|- | |- | ||
| style="background: #DCDCDC; padding: 5px; text-align: center;" |<small>Inflammatory bowel disease</small> | | style="background: #DCDCDC; padding: 5px; text-align: center;" |<small>Inflammatory bowel disease</small> |
Revision as of 03:59, 3 September 2021
Angiodysplasia Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief:
Overview
Angiodysplasia must be differentiated from other diseases that cause hematochezia, melena, and iron deficiency anemia , such as hemorrhoids, diverticular disease and colon cancer.
Differentiating Angiodysplasia from other Diseases
Angiodysplasia must be differentiated from diverticulitis, hemorrhoids, colon cancer, massive upper GI bleed and inflammatory bowel disease.
Diseases | Clinical manifestations | Para-clinical findings | Gold standard | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Symptoms | Physical examination | |||||||||||||
Lab Findings | Imaging | Histopathology | ||||||||||||
Symptom 1 | Symptom 2 | Symptom 3 | Physical exam 1 | Physical exam 2 | Physical exam 3 | Lab 1 | Lab 2 | Lab 3 | Imaging 1 | Imaging 2 | Imaging 3 | |||
Diverticulitis | Abdominal cramps | Bloating | Diarrhoea | Left lower quadrant abdominal tenderness | Bowel sounds hypoactive/normoactive | Fever | Leukocytosis | Elevated ESR and CRP | Radiological test of choice - CT of abdomen and pelvis with contrast | Abdominal Ultrasound | MRI abdomen | Colonoscopy after resolution of inflammation | ||
Hemorrhoids | Hematochezia | Anal pain | Anal protrusion | Skin tags | Fistulas or fissures | Prolapsed hemorrhoid | External hemorrhoids - distal to dentate line.
Internal hemorrhoids - proximal to dentate line. |
Anoscopy | ||||||
Colon cancer | Tenesmus | Bowel habits change | Weight loss | Lmyphadenopathies | Abdominal mass | Hepatomegaly (metastasis) | Tumor marker - CEA | CT with contrast chest, abdomen and pelvis | Majority of colorectal cancers are carcinomas. | Colonoscopy | ||||
Massive upper GI bleed | Hematemesis | Abdominal pain | Melena | Hemodynamic instability | Upper abdominal tenderness | Pale skin | Acute bleeding - normocytic anemia | Elevated BUN-to-Creatinine ratio >30:1 | CT angiography | Endoscopy | ||||
Inflammatory bowel disease | ||||||||||||||
Angiodysplasia |