Fragile X syndrome historical perspective: Difference between revisions
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== Overview == | ==Overview== | ||
James Purdon Martin and Julia Bell first described fragile X syndrome in 1943. A case study of family showed intellectual disability appeared to be inherited and linked to the X chromosome. Later in 1969, Herbert Lubs observed a characteristic fragile site on the lower end of the X chromosome, which was responsible for the disease. | James Purdon Martin and Julia Bell first described [[fragile X syndrome]] in 1943. A case study of family showed [[intellectual disability]] appeared to be [[inherited]] and linked to the X chromosome. Later in 1969, Herbert Lubs observed a characteristic [[fragile site]] on the lower end of the [[X chromosome|X chromosome,]] which was responsible for the disease. | ||
== Historical Perspective == | ==Historical Perspective== | ||
Fragile X syndrome was described first by Martin and Bell in 1943. | Fragile X syndrome was described first by Martin and Bell in 1943. | ||
== References == | ==References== | ||
Martin JP, Bell J. A pedigree of mental defect showing sex- linkage. J Neurol Psychiatry. 1943; 6(3-4): 154–7 | Martin JP, Bell J. A pedigree of mental defect showing sex- linkage. J Neurol Psychiatry. 1943; 6(3-4): 154–7 |
Revision as of 20:37, 3 September 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
James Purdon Martin and Julia Bell first described fragile X syndrome in 1943. A case study of family showed intellectual disability appeared to be inherited and linked to the X chromosome. Later in 1969, Herbert Lubs observed a characteristic fragile site on the lower end of the X chromosome, which was responsible for the disease.
Historical Perspective
Fragile X syndrome was described first by Martin and Bell in 1943.
References
Martin JP, Bell J. A pedigree of mental defect showing sex- linkage. J Neurol Psychiatry. 1943; 6(3-4): 154–7