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==Overview==
==Overview==

Revision as of 10:39, 15 October 2021

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Nikita Singh, M.B.B.S.[2]

Overview

Angiodysplasia was first reported in 1839 by Phillips as a vascular lesion causing bleeding from large intestine. Heyde discovered the association between aortic stenosis and angiodysplasia in 1958. The term angiodysplasia was coined by Galdabini in 1974.

Historical Perspective

Discovery

  • Angiodysplasia was first reported in 1839 by Phillips as a vascular lesion causing bleeding from large intestine.
  • Dr. E.C. Heyde discovered the association between aortic stenosis and angiodysplasia in 1958.[1]
  • Margulis, while performing operative mesenteric arteriography on a patient who presented with massive bleeding, detected a vascular malformation in the large bowel in 1960.
  • The term angiodysplasia was coined by Galdabini in 1974.[2]
  • The association between gastrointestinal bleeding in angiodysplasia and von Willebrand disease was first described by Ramsey et al in 1976.[3][4]

References

  1. Hasan F, O'Brien CS, Sanyal A, Dalton HR (2004). "Aortic stenosis and gastrointestinal bleeding". J R Soc Med. 97 (2): 81–2. doi:10.1258/jrsm.97.2.81. PMC 1079297. PMID 14749406.
  2. Athanasoulis CA, Galdabini JJ, Waltman AC, Novelline RA, Greenfield AJ, Ezpeleta ML (1977). "Angiodysplasia of the colon: a cause of rectal bleeding". Cardiovasc Radiol. 1 (1): 3–13. doi:10.1007/BF02551967. PMID 311247.
  3. Selvam S, James P (2017). "Angiodysplasia in von Willebrand Disease: Understanding the Clinical and Basic Science". Semin Thromb Hemost. 43 (6): 572–580. doi:10.1055/s-0037-1599145. PMC 5949878. PMID 28476066.
  4. Ramsay DM, Buist TA, Macleod DA, Heading RC (1976). "Persistent gastrointestinal bleeding due to angiodysplasia of the gut in von Willebrand's disease". Lancet. 2 (7980): 275–8. doi:10.1016/s0140-6736(76)90729-7. PMID 59851.

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