Angiodysplasia natural history, complications and prognosis: Difference between revisions
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==Natural History== | ==Natural History== | ||
* Small bowel angiodysplasia (SBA) contributes to 50% of obscure GI bleeding. | * Small bowel angiodysplasia (SBA) contributes to 50% of obscure GI bleeding.<ref name="pmid26540240">{{cite journal| author=Holleran G, Hall B, Zgaga L, Breslin N, McNamara D| title=The natural history of small bowel angiodysplasia. | journal=Scand J Gastroenterol | year= 2016 | volume= 51 | issue= 4 | pages= 393-9 | pmid=26540240 | doi=10.3109/00365521.2015.1102317 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26540240 }} </ref> | ||
* SBA tends to re-bleed more than angiodysplasia of the colon and stomach. | * SBA tends to re-bleed more than angiodysplasia of the colon and stomach. | ||
* In a retrospective study, re-bleeding occurred after about 11 months of diagnosis in 80% of patients, and 3.5% died as a direct result of bleeding. | * In a retrospective study, re-bleeding occurred after about 11 months of diagnosis in 80% of patients, and 3.5% died as a direct result of bleeding. | ||
* Multiple lesions and valvular heart diseases have been found to increase the risk of re-bleeding. | * Multiple lesions and valvular heart diseases have been found to increase the risk of re-bleeding.<ref name="pmid26540240">{{cite journal| author=Holleran G, Hall B, Zgaga L, Breslin N, McNamara D| title=The natural history of small bowel angiodysplasia. | journal=Scand J Gastroenterol | year= 2016 | volume= 51 | issue= 4 | pages= 393-9 | pmid=26540240 | doi=10.3109/00365521.2015.1102317 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=26540240 }} </ref> | ||
* Apart from recurrence of bleeding, some other concerns in the natural history of angiodysplasia are transfusion requirements, hospital readmissions, and requirement endoscopic, pharmacological, or surgical therapy. | * Apart from recurrence of bleeding, some other concerns in the natural history of angiodysplasia are transfusion requirements, hospital readmissions, and requirement endoscopic, pharmacological, or surgical therapy. | ||
* In asymptomatic people, the course of angiodysplasia is benign, and the bleeding risk is low. Consequently, treatment is not required for incidentally found lesions. | * In asymptomatic people, the course of angiodysplasia is benign, and the bleeding risk is low. Consequently, treatment is not required for incidentally found lesions.<ref name="pmid7717311">{{cite journal| author=Foutch PG, Rex DK, Lieberman DA| title=Prevalence and natural history of colonic angiodysplasia among healthy asymptomatic people. | journal=Am J Gastroenterol | year= 1995 | volume= 90 | issue= 4 | pages= 564-7 | pmid=7717311 | doi= | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=7717311 }} </ref> | ||
==Complications== | ==Complications== | ||
Revision as of 12:51, 14 September 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Nikita Singh, M.D.[2]
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Overview
Natural History
- Small bowel angiodysplasia (SBA) contributes to 50% of obscure GI bleeding.[1]
- SBA tends to re-bleed more than angiodysplasia of the colon and stomach.
- In a retrospective study, re-bleeding occurred after about 11 months of diagnosis in 80% of patients, and 3.5% died as a direct result of bleeding.
- Multiple lesions and valvular heart diseases have been found to increase the risk of re-bleeding.[1]
- Apart from recurrence of bleeding, some other concerns in the natural history of angiodysplasia are transfusion requirements, hospital readmissions, and requirement endoscopic, pharmacological, or surgical therapy.
- In asymptomatic people, the course of angiodysplasia is benign, and the bleeding risk is low. Consequently, treatment is not required for incidentally found lesions.[2]
Complications
- Anemia
- Death from excessive blood loss
- Side effects from treatment
- Severe loss of blood from the GI tract
Prognosis
Patients who have bleeding related to this condition despite having had a colonoscopy, angiography, or surgery are likely to have more bleeding in the future. The outlook remains good if the bleeding is controlled.
References
- ↑ 1.0 1.1 Holleran G, Hall B, Zgaga L, Breslin N, McNamara D (2016). "The natural history of small bowel angiodysplasia". Scand J Gastroenterol. 51 (4): 393–9. doi:10.3109/00365521.2015.1102317. PMID 26540240.
- ↑ Foutch PG, Rex DK, Lieberman DA (1995). "Prevalence and natural history of colonic angiodysplasia among healthy asymptomatic people". Am J Gastroenterol. 90 (4): 564–7. PMID 7717311.