Pyonephrosis laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
The initial workup done when suspecting a case of pyonephrosis include urinalysis and culture, complete blood count with differentials, and blood culture. The urine and blood samples for culture must be obtained prior to starting the antibiotic therapy. | The initial workup done when suspecting a case of pyonephrosis include urinalysis and culture which may show white blood cells, bacteria, and pus cells; complete blood count with differentials showing neutrophilia, and blood culture which may be positive if bacteremia has already occurred. The urine and blood samples for culture must be obtained prior to starting the antibiotic therapy. | ||
==Laboratory findings== | ==Laboratory findings== | ||
Revision as of 09:19, 17 October 2021
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Harsh Vardhan Chawla, M.B.B.S.[2]
Overview
The initial workup done when suspecting a case of pyonephrosis include urinalysis and culture which may show white blood cells, bacteria, and pus cells; complete blood count with differentials showing neutrophilia, and blood culture which may be positive if bacteremia has already occurred. The urine and blood samples for culture must be obtained prior to starting the antibiotic therapy.
Laboratory findings
The initial workup done when suspecting a case of pyonephrosis are the following[1][2]:
Urinalysis and culture
Urine samples must be collected before starting the antibiotic therapy to avoid false-negative results.
If percutaneous nephrostomy is done, the sample must be collected from the site above the obstruction
The presence of white blood cells, bacteria, pus cells in the urine may indicate pyonephrosis.
Cultures must be sent for gram stain, fungal pathogens, and acid-fast stain (if tuberculosis is suspected).
Complete Blood Count (CBC)
CBC with differential count should be obtained which will reveal leukocytosis with neutrophilia.
Blood Culture
Blood samples should also be collected prior to starting the antibiotic therapy to avoid false-negative results.
Blood cultures will be positive in pyonephrosis if the infection has spread to the bloodstream.
References
- ↑ Subramanyam BR, Raghavendra BN, Bosniak MA, Lefleur RS, Rosen RJ, Horii SC (1983). "Sonography of pyonephrosis: a prospective study". AJR Am J Roentgenol. 140 (5): 991–3. doi:10.2214/ajr.140.5.991. PMID 6601449.
- ↑ Bitsori M, Raissaki M, Maraki S, Galanakis E (2015). "Acute focal bacterial nephritis, pyonephrosis and renal abscess in children". Pediatr Nephrol. 30 (11): 1987–93. doi:10.1007/s00467-015-3141-3. PMID 26076753.