Cavernous angioma history and symptoms: Difference between revisions
Jump to navigation
Jump to search
Line 7: | Line 7: | ||
==Overview== | ==Overview== | ||
* Clinical symptoms of this disease include: | *Clinical symptoms of this disease include: | ||
** recurrent [[headache]]s, | **recurrent [[headache]]s, | ||
** focal neurological deficits, | **focal neurological deficits, | ||
** hemorrhagic [[stroke]] | **hemorrhagic [[stroke]] | ||
** [[seizures]] | **[[seizures]] | ||
* CCM can also be [[asymptomatic]]. Familial forms can present asymptomatically, however, when it becomes symptomatic, seizure is the most common symptom. <ref name="pmid30909834">{{cite journal| author=Zafar A, Quadri SA, Farooqui M, Ikram A, Robinson M, Hart BL | display-authors=etal| title=Familial Cerebral Cavernous Malformations. | journal=Stroke | year= 2019 | volume= 50 | issue= 5 | pages= 1294-1301 | pmid=30909834 | doi=10.1161/STROKEAHA.118.022314 | pmc=6924279 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30909834 }} </ref> | *CCM can also be [[asymptomatic]]. Familial forms can present asymptomatically, however, when it becomes symptomatic, seizure is the most common symptom. <ref name="pmid30909834">{{cite journal| author=Zafar A, Quadri SA, Farooqui M, Ikram A, Robinson M, Hart BL | display-authors=etal| title=Familial Cerebral Cavernous Malformations. | journal=Stroke | year= 2019 | volume= 50 | issue= 5 | pages= 1294-1301 | pmid=30909834 | doi=10.1161/STROKEAHA.118.022314 | pmc=6924279 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=30909834 }} </ref> | ||
==History and Symptoms== | ==History and Symptoms== | ||
* This disease is characterized by grossly dilated blood vessels with a single layer of [[endothelium]] and an absence of neuronal tissue within the lesions. | *This disease is characterized by grossly dilated blood vessels with a single layer of [[endothelium]] and an absence of neuronal tissue within the lesions. | ||
* These thinly-walled vessels resemble sinusoidal cavities filled with stagnant blood. | *These thinly-walled vessels resemble sinusoidal cavities filled with stagnant blood. | ||
* Blood vessels in patients with CCM can range from a few millimeters to several centimeters in diameter. CCM lesions commonly resemble raspberries in external structure. | *Blood vessels in patients with CCM can range from a few millimeters to several centimeters in diameter. CCM lesions commonly resemble raspberries in external structure. | ||
* Many patients live their whole life without knowing they have a cerebral cavernous malformation. | *Many patients live their whole life without knowing they have a cerebral cavernous malformation. | ||
* Other patients can have severe symptoms like seizures, headaches, paralysis, bleeding in the brain ([[cerebral hemorrhage]], or [[hemorrhagic stroke]]), and even death. | *Other patients can have severe symptoms like seizures, headaches, paralysis, bleeding in the brain ([[cerebral hemorrhage]], or [[hemorrhagic stroke]]), and even death. | ||
* The nature and severity of the symptoms depend on the lesion's location in the brain. Approximately 70% of these lesions occur in the [[supratentorial]] region of the brain | *The nature and severity of the symptoms depend on the lesion's location in the brain. Approximately 70% of these lesions occur in the [[supratentorial]] region of the brain. | ||
*The remaining 30% occur in the infratentorial region. | |||
==References== | ==References== |
Revision as of 07:54, 26 February 2022
Cavernous angioma Microchapters |
Diagnosis |
---|
Treatment |
Case Studies |
Cavernous angioma history and symptoms On the Web |
American Roentgen Ray Society Images of Cavernous angioma history and symptoms |
Risk calculators and risk factors for Cavernous angioma history and symptoms |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Please help WikiDoc by adding more content here. It's easy! Click here to learn about editing.
Overview
- Clinical symptoms of this disease include:
- CCM can also be asymptomatic. Familial forms can present asymptomatically, however, when it becomes symptomatic, seizure is the most common symptom. [1]
History and Symptoms
- This disease is characterized by grossly dilated blood vessels with a single layer of endothelium and an absence of neuronal tissue within the lesions.
- These thinly-walled vessels resemble sinusoidal cavities filled with stagnant blood.
- Blood vessels in patients with CCM can range from a few millimeters to several centimeters in diameter. CCM lesions commonly resemble raspberries in external structure.
- Many patients live their whole life without knowing they have a cerebral cavernous malformation.
- Other patients can have severe symptoms like seizures, headaches, paralysis, bleeding in the brain (cerebral hemorrhage, or hemorrhagic stroke), and even death.
- The nature and severity of the symptoms depend on the lesion's location in the brain. Approximately 70% of these lesions occur in the supratentorial region of the brain.
- The remaining 30% occur in the infratentorial region.
References
- ↑ Zafar A, Quadri SA, Farooqui M, Ikram A, Robinson M, Hart BL; et al. (2019). "Familial Cerebral Cavernous Malformations". Stroke. 50 (5): 1294–1301. doi:10.1161/STROKEAHA.118.022314. PMC 6924279 Check
|pmc=
value (help). PMID 30909834.