Cardiac tumors laboratory tests: Difference between revisions

Jump to navigation Jump to search
Line 12: Line 12:
*Some patients with cardiac tumors may have anemia, less commonly thrombocytopenia, increases in sedimentation rate, serum C-reactive protein level, or globulin level. These are nonspecific diagnostic anomalies.<ref name="pmid33040219">{{cite journal| author=Bussani R, Castrichini M, Restivo L, Fabris E, Porcari A, Ferro F | display-authors=etal| title=Cardiac Tumors: Diagnosis, Prognosis, and Treatment. | journal=Curr Cardiol Rep | year= 2020 | volume= 22 | issue= 12 | pages= 169 | pmid=33040219 | doi=10.1007/s11886-020-01420-z | pmc=7547967 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=33040219  }} </ref>
*Some patients with cardiac tumors may have anemia, less commonly thrombocytopenia, increases in sedimentation rate, serum C-reactive protein level, or globulin level. These are nonspecific diagnostic anomalies.<ref name="pmid33040219">{{cite journal| author=Bussani R, Castrichini M, Restivo L, Fabris E, Porcari A, Ferro F | display-authors=etal| title=Cardiac Tumors: Diagnosis, Prognosis, and Treatment. | journal=Curr Cardiol Rep | year= 2020 | volume= 22 | issue= 12 | pages= 169 | pmid=33040219 | doi=10.1007/s11886-020-01420-z | pmc=7547967 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=33040219  }} </ref>
*Antimyolemmal antibodies could also be elevated.  Antimyolemmal antibodies are significantly more prevalent in chronic pericardial effusion, perimyocarditis, and dilated cardiomyopathy patients than healthy controls.
*Antimyolemmal antibodies could also be elevated.  Antimyolemmal antibodies are significantly more prevalent in chronic pericardial effusion, perimyocarditis, and dilated cardiomyopathy patients than healthy controls.
*Antiendothelial antibodies of the IgG type are detected in 86 percent of atrial myxoma patients. Endothelial cells are activated by Antiendothelial antibodies, leading to enhanced leukocyte adhesion, clotting activation, and vessel thrombosis.
*Antiendothelial antibodies of the IgG type are detected in 86 percent of atrial myxoma patients. Endothelial cells are activated by Antiendothelial antibodies, leading to enhanced leukocyte adhesion, clotting activation, and vessel thrombosis.<ref name="pmid16569688">{{cite journal| author=Belizna C, Duijvestijn A, Hamidou M, Tervaert JW| title=Antiendothelial cell antibodies in vasculitis and connective tissue disease. | journal=Ann Rheum Dis | year= 2006 | volume= 65 | issue= 12 | pages= 1545-50 | pmid=16569688 | doi=10.1136/ard.2005.035295 | pmc=1798473 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16569688  }} </ref>


===Imaging===
===Imaging===

Revision as of 23:57, 14 May 2022

Cardiac tumors Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Cardiac Tumors from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

Chest X Ray

CT

MRI

Echocardiography or Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Cardiac tumors laboratory tests On the Web

Most recent articles

Most cited articles

Review articles

CME Programs

Powerpoint slides

Images

American Roentgen Ray Society Images of Cardiac tumors laboratory tests

All Images
X-rays
Echo & Ultrasound
CT Images
MRI

Ongoing Trials at Clinical Trials.gov

US National Guidelines Clearinghouse

NICE Guidance

FDA on Cardiac tumors laboratory tests

CDC on Cardiac tumors laboratory tests

Cardiac tumors laboratory tests in the news

Blogs on Cardiac tumors laboratory tests

Directions to Hospitals Treating Cardiac tumors

Risk calculators and risk factors for Cardiac tumors laboratory tests

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Template:Dj

Overview

Laboratory Findings

Template:Cardiac Tumors Editor-In-Chief: C. Michael Gibson, M.S., M.D. [2]; Associate Editor(s)-in-Chief: Template:Dj


Blood Investigations

  • Some patients with cardiac tumors may have anemia, less commonly thrombocytopenia, increases in sedimentation rate, serum C-reactive protein level, or globulin level. These are nonspecific diagnostic anomalies.[1]
  • Antimyolemmal antibodies could also be elevated. Antimyolemmal antibodies are significantly more prevalent in chronic pericardial effusion, perimyocarditis, and dilated cardiomyopathy patients than healthy controls.
  • Antiendothelial antibodies of the IgG type are detected in 86 percent of atrial myxoma patients. Endothelial cells are activated by Antiendothelial antibodies, leading to enhanced leukocyte adhesion, clotting activation, and vessel thrombosis.[2]

Imaging

  • The CXR can detect cardiomegaly. A localized tumor prominence may or may not be present.
  • On echocardiography, a massive, noncontractile, firm lump may be observed in the atrial or ventricular walls. It is more useful in diagnosing myxomas as compared to sarcomas.
  • Doppler ultrasonography measures of velocities can be used to calculate chamber pressures.
  • Transesophageal echocardiography (TEE) is appropriate for evaluating malignancies anticipated to include the atria, interatrial septum, superior vena cava, atrioventricular valves, and, to a minor degree, the ventricles.
  • CT and Cardiac MRI(CMR)are helpful for resectability evaluation.
  • PET can be utilized to detect cardiovascular spread in patients with metastatic malignancies and enables surgical treatment.
    • Imaging tests individually cannot determine if a heart tumor is benign or malignant; histologic assessment is required for a definite diagnosis.

References

  1. Bussani R, Castrichini M, Restivo L, Fabris E, Porcari A, Ferro F; et al. (2020). "Cardiac Tumors: Diagnosis, Prognosis, and Treatment". Curr Cardiol Rep. 22 (12): 169. doi:10.1007/s11886-020-01420-z. PMC 7547967 Check |pmc= value (help). PMID 33040219 Check |pmid= value (help).
  2. Belizna C, Duijvestijn A, Hamidou M, Tervaert JW (2006). "Antiendothelial cell antibodies in vasculitis and connective tissue disease". Ann Rheum Dis. 65 (12): 1545–50. doi:10.1136/ard.2005.035295. PMC 1798473. PMID 16569688.

Template:WH Template:WS