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|'''[[Hamartoma of Cardiac Myocytes]]''' || Lesions are defined histologically by a  
|'''[[Hamartoma of Cardiac Myocytes]]''' || Lesions are defined histologically by a  
*nodular cluster of enlarged, highly disordered cardiomyocytes.<ref name="pmid18455585">{{cite journal| author=ElBardissi AW, Dearani JA, Daly RC, Mullany CJ, Orszulak TA, Puga FJ | display-authors=etal| title=Analysis of benign ventricular tumors: long-term outcome after resection. | journal=J Thorac Cardiovasc Surg | year= 2008 | volume= 135 | issue= 5 | pages= 1061-8 | pmid=18455585 | doi=10.1016/j.jtcvs.2007.10.048 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18455585  }} </ref>
*nodular cluster of enlarged, highly disordered cardiomyocytes.<ref name="pmid18455585">{{cite journal| author=ElBardissi AW, Dearani JA, Daly RC, Mullany CJ, Orszulak TA, Puga FJ | display-authors=etal| title=Analysis of benign ventricular tumors: long-term outcome after resection. | journal=J Thorac Cardiovasc Surg | year= 2008 | volume= 135 | issue= 5 | pages= 1061-8 | pmid=18455585 | doi=10.1016/j.jtcvs.2007.10.048 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18455585  }} </ref>
|-
|Undifferentiated Pleomorphic Sarcoma || Histopathologic features of Undifferentiated Pleomorphic Sarcoma are
*Typical spindle and polygonal (strap-like) cells filled with an eosinophilic cytoplasm
*Desmin- and myoglobin-positive
*CD68 negative<ref name="pmid14745155">{{cite journal| author=Nakagawa Y, Ikeda U, Hirose M, Ubukata S, Katsuki TA, Kaminishi Y | display-authors=etal| title=Successful treatment of primary cardiac lymphoma with monoclonal CD20 antibody (rituximab). | journal=Circ J | year= 2004 | volume= 68 | issue= 2 | pages= 172-3 | pmid=14745155 | doi=10.1253/circj.68.172 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=14745155  }} </ref>
|}
|}


Revision as of 22:40, 18 May 2022

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Template:Dj

Overview

Cardiac Tumors Biopsy Findings

Biopsy findings associated with cardiac tumors include the following:
Cardiac Tumors Biopsy Findings
Tumor Biopsy Findings
Myxoma Hemorrhages, spindle or stellate cells, pseudovascular structure, myxoid matrix.
  • There may be dystrophic calcification present.
Cardiac Lipoma Histopathologically, a cardiac lipoma is constituted of
  • mature fat cells, fibrous connective tissue, and
  • vacuolated brown fat.
Cardiac Fibroma Histologically, fibromas are predominantly made of
  • fibroblasts or collagen, with the characteristic "spindle cells."
  • Calcification of fibromas is especially prevalent among elderly people
Fibroelastoma Histopathologically, a cardiac lipoma is constituted of
  • endocardium-coated fronds contain an avascular collagenous core.
Rhabdomyoma Cardiac rhabdomyomas are characterized by
  • classic spider cells, polygonal myocytes with conspicuous sarcoplasmic clearing.
  • Rhabdomyomas are formed of enlarged, vacuolated cardiomyocytes.
Fibroelastomas
  • It consists of endocardium-coated fronds surrounding an avascular collagenous core.[1]
Mesothelioma Histopathology Mesothelioma cells can exhibit three different configurations,
  • namely largely epithelial, mostly fibrous (spindle cell), and biphasic (mixed).
  • Carcinoembryonic antigen (CEA) and positive mesothelial markers (calretinin and cytokeratins) may effectively distinguish mesotheliomas from pericardial metastases of adenocarcinoma.[2]
Cystic Tumor of the Atrioventricular Node The tumor is found on the right side of the central fibrous body, invading and squeezing the AV node histologically.
  • The lesions are packed by a mucoid  material and are bordered by epithelium, cytokeratin, and epithelial membrane antigen positive.[3]
Hemangioma histologically characterized
  • by small capillaries (capillary hemangioma), big vessels (cavernous hemangioma, the most frequent kind), or dysplastic vessels (cirsoid aneurysm).
Hamartoma of Cardiac Myocytes Lesions are defined histologically by a
  • nodular cluster of enlarged, highly disordered cardiomyocytes.[4]
Undifferentiated Pleomorphic Sarcoma Histopathologic features of Undifferentiated Pleomorphic Sarcoma are
  • Typical spindle and polygonal (strap-like) cells filled with an eosinophilic cytoplasm
  • Desmin- and myoglobin-positive
  • CD68 negative[5]

References

  1. ↑ Maleszewski JJ, Anavekar NS, Moynihan TJ, Klarich KW (2017). "Pathology, imaging, and treatment of cardiac tumours". Nat Rev Cardiol. 14 (9): 536–549. doi:10.1038/nrcardio.2017.47. PMID 28436488.
  2. ↑ Nilsson A, Rasmuson T (2009). "Primary Pericardial Mesothelioma: Report of a Patient and Literature Review". Case Rep Oncol. 2 (2): 125–132. doi:10.1159/000228894. PMC 2918860. PMID 20740175.
  3. ↑ Moorjani N, Kuo J, Wilkins D (2004). "Left atrial phaeochromocytoma". Heart. 90 (11): e64. doi:10.1136/hrt.2004.041319. PMC 1768537. PMID 15486108.
  4. ↑ ElBardissi AW, Dearani JA, Daly RC, Mullany CJ, Orszulak TA, Puga FJ; et al. (2008). "Analysis of benign ventricular tumors: long-term outcome after resection". J Thorac Cardiovasc Surg. 135 (5): 1061–8. doi:10.1016/j.jtcvs.2007.10.048. PMID 18455585.
  5. ↑ Nakagawa Y, Ikeda U, Hirose M, Ubukata S, Katsuki TA, Kaminishi Y; et al. (2004). "Successful treatment of primary cardiac lymphoma with monoclonal CD20 antibody (rituximab)". Circ J. 68 (2): 172–3. doi:10.1253/circj.68.172. PMID 14745155.

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