Cardiac tumors causes: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Cardiac tumors}} | {{Cardiac tumors}} | ||
{{CMG}} | {{CMG}}; {{AE}} {{Dj}} | ||
==Overview== | ==Overview== | ||
==Causes== | ==Causes== |
Revision as of 04:06, 7 June 2022
Cardiac tumors Microchapters |
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Cardiac tumors causes On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Template:Dj
Overview
Causes
- Many genetic conditions are strongly associated with a large number of heart tumors. Some of them are as follows:[1]
Tumor | Syndrome | Gene Associated with syndrome |
---|---|---|
Rhabdomyoma | Tuberous Sclerosis | TSC1 or hamartin
TSC2 or tuberin |
Fibroma | Gorlin Syndrome | PATCHED gene |
Myxoma | Carney Complex | Inactivating mutation of PRKARA1A
Activating pathogenic variant of PRKACA gene |
Paraganglioma | Carney triad | No known gene associations |
Paraganglioma | Hereditary Paraganglioma | Mutation of succinate dehydrogenase subunit
SDHAF2 gene, and possibly MAX gene but these mutations are rare |
Paraganglioma | Von Hippel Lindau | VHL gene |
Paraganglioma | Neurofibromatosis type 1 | NF1 gene |
References
- ↑ Lee E, Mahani MG, Lu JC, Dorfman AL, Srinivasan A, Agarwal PP (2018). "Primary cardiac tumors associated with genetic syndromes: a comprehensive review". Pediatr Radiol. 48 (2): 156–164. doi:10.1007/s00247-017-4027-2. PMID 29214333.