Amiodarone overdose: Difference between revisions
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New page: {{CMG}} There have been cases, some fatal, of Amiodarone overdose. In addition to general supportive measures, the patient's cardiac rhythm and blood pressure should be monitored, and if... |
m Protected "Amiodarone overdose" [edit=sysop:move=sysop] |
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Revision as of 20:19, 8 January 2009
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
There have been cases, some fatal, of Amiodarone overdose.
In addition to general supportive measures, the patient's cardiac rhythm and blood pressure should be monitored, and if bradycardia ensues, a β-adrenergic agonist or a pacemaker may be used. Hypotension with inadequate tissue perfusion should be treated with positive inotropic and/or vasopressor agents. Neither Amiodarone nor its metabolite is dialyzable.
The acute oral LD50 of Amiodarone HCl in mice and rats is greater than 3,000 mg/kg.