Atenolol overdose: Difference between revisions

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#REDIRECT [[Atenolol#Overdosage]]
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==Overdosage topics==
 
Overdosage with Atenolol has been reported with patients surviving acute doses as high as 5 g. One death was reported in a man who may have taken as much as 10 g acutely.
 
The predominant symptoms reported following Atenolol overdose are [[lethargy]], disorder of respiratory drive, [[wheezing]], [[sinus pause]] and [[bradycardia]]. Additionally, common effects associated with overdosage of any beta-adrenergic blocking agent and which might also be expected in Atenolol overdose are [[congestive heart failure]], [[hypotension]], [[bronchospasm]] and/or [[hypoglycemia]].
 
Treatment of overdose should be directed to the removal of any unabsorbed drug by induced emesis, gastric lavage, or administration of activated charcoal. Atenolol can be removed from the general circulation by hemodialysis. Other treatment modalities should be employed at the physician's discretion and may include:
 
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<font size="4">[[Atenolol overdose#Bradycardia|Bradycardia]]</font>
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<font size="4">[[Atenolol overdose#Heart Block (Second or Third Degree)|Heart Block (Second or Third Degree)]]</font>
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<font size="4">[[Atenolol overdose#Cardiac Failure|Cardiac Failure]]</font>
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<font size="4">[[Atenolol overdose#Hypotension|Hypotension]]</font>
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<font size="4">[[Atenolol overdose#Bronchospasm|Bronchospasm]]</font>
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<font size="4">[[Atenolol overdose#Hypoglycemia|Hypoglycemia]]</font>
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===Bradycardia===
 
Atropine intravenously. If there is no response to vagal blockade, give isoproterenol cautiously. In refractory cases, a transvenous cardiac pacemaker may be indicated.
 
''[[Atenolol overdose#List of overdosage topics|Return to top]]''
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===Heart Block (Second or Third Degree)===
 
[[Isoproterenol]] or [[transvenous cardiac pacemaker]].
 
''[[Atenolol overdose#List of overdosage topics|Return to top]]''
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===Cardiac Failure===
 
[[Digitalize]] the patient and administer a [[diuretic]]. [[Glucagon]] has been reported to be useful.
 
''[[Atenolol overdose#List of overdosage topics|Return to top]]''
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===Hypotension===
 
Vasopressors such as [[dopamine]] or [[norepinephrine]] ([[levarterenol]]). Monitor blood pressure continuously.
 
''[[Atenolol overdose#List of overdosage topics|Return to top]]''
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===Bronchospasm===
 
A beta-2 stimulant such as [[isoproterenol]] or [[terbutaline]] and/or [[aminophylline]].
 
''[[Atenolol overdose#List of overdosage topics|Return to top]]''
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===Hypoglycemia===
 
Intravenous [[glucose]].
 
Based on the severity of symptoms, management may require intensive support care and facilities for applying cardiac and respiratory support.
 
''[[Atenolol overdose#List of overdosage topics|Return to top]]''
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{{FDA}}
 
 
 
 
[[Category:Drugs]]

Latest revision as of 23:49, 21 July 2014