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| {{CMG}}
| | #REDIRECT [[Propranolol#Overdosage]] |
| ==Overdosage topics==
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| Propranolol is not significantly dialyzable. In the event of overdosage or exaggerated response, the following measures should be employed:
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| <font size="4">[[Propranolol overdose#General|General]]</font>
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| <font size="4">[[Propranolol overdose#Supportive Therapy|Supportive Therapy]]</font>
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| ----
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| ===General===
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| If ingestion is or may have been recent, evacuate gastric contents, taking care to prevent [[pulmonary aspiration]].
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| ''[[Propranolol overdose#Overdosage topics|Return to top]]''
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| ===Supportive Therapy===
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| [[Hypotension]] and [[bradycardia]] have been reported following Propranolol overdose and should be treated appropriately.
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| [[Glucagon]] can exert potent inotropic and chronotropic effects and may be particularly useful for the treatment of hypotension or depressed myocardial function after a Propranolol overdose. [[Glucagon]] should be administered as 50-150 mcg/kg intravenously followed by continuous drip of 1-5 mg/hour for positive chronotropic effect.
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| [[Isoproterenol]], [[dopamine]] or [[phosphodiesterase inhibitors]] may also be useful. [[Epinephrine]], however, may provoke uncontrolled [[hypertension]].
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| [[Bradycardia]] can be treated with [[atropine]] or [[isoproterenol]].
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| Serious [[bradycardia]] may require [[temporary cardiac pacing]].
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| The [[electrocardiogram]], [[pulse]], [[blood pressure]], neurobehavioral status and intake and output balance must be monitored.
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| [[Isoproterenol]] and [[aminophylline]] may be used for [[bronchospasm]].
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| ''[[Propranolol overdose#Overdosage topics|Return to top]]''
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| {{FDA}}
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| [[Category:Drugs]]
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