ACTR1B: Difference between revisions
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| Line 19: | Line 19: | ||
| OMIM = 605144 | | OMIM = 605144 | ||
| ECnumber = | | ECnumber = | ||
| Homologene = | | Homologene = 101541 | ||
| MGIid = 1917446 | | MGIid = 1917446 | ||
| Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005198 |text = structural molecule activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} | | Function = {{GNF_GO|id=GO:0000166 |text = nucleotide binding}} {{GNF_GO|id=GO:0005198 |text = structural molecule activity}} {{GNF_GO|id=GO:0005515 |text = protein binding}} {{GNF_GO|id=GO:0005524 |text = ATP binding}} | ||
| Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005856 |text = cytoskeleton}} {{GNF_GO|id=GO:0005869 |text = dynactin complex}} | | Component = {{GNF_GO|id=GO:0005737 |text = cytoplasm}} {{GNF_GO|id=GO:0005856 |text = cytoskeleton}} {{GNF_GO|id=GO:0005869 |text = dynactin complex}} | ||
| Line 30: | Line 27: | ||
| Hs_EntrezGene = 10120 | | Hs_EntrezGene = 10120 | ||
| Hs_Ensembl = ENSG00000115073 | | Hs_Ensembl = ENSG00000115073 | ||
| Hs_RefseqProtein = | | Hs_RefseqProtein = NP_005726 | ||
| Hs_RefseqmRNA = | | Hs_RefseqmRNA = NM_005735 | ||
| Hs_GenLoc_db = | | Hs_GenLoc_db = | ||
| Hs_GenLoc_chr = 2 | | Hs_GenLoc_chr = 2 | ||
| Line 39: | Line 36: | ||
| Mm_EntrezGene = 226977 | | Mm_EntrezGene = 226977 | ||
| Mm_Ensembl = ENSMUSG00000037351 | | Mm_Ensembl = ENSMUSG00000037351 | ||
| Mm_RefseqmRNA = | | Mm_RefseqmRNA =146107 | ||
| Mm_RefseqProtein = | | Mm_RefseqProtein =666219 | ||
| Mm_GenLoc_db = | | Mm_GenLoc_db = | ||
| Mm_GenLoc_chr = 1 | | Mm_GenLoc_chr = 1 | ||
Revision as of 21:24, 3 March 2009
| ARP1 actin-related protein 1 homolog B, centractin beta (yeast) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||
| Symbols | ACTR1B ; ARP1 | ||||||||||
| External IDs | Template:OMIM5 Template:MGI HomoloGene: 101541 | ||||||||||
| |||||||||||
| Orthologs | |||||||||||
| Template:GNF Ortholog box | |||||||||||
| Species | Human | Mouse | |||||||||
| Entrez | n/a | n/a | |||||||||
| Ensembl | n/a | n/a | |||||||||
| UniProt | n/a | n/a | |||||||||
| RefSeq (mRNA) | n/a | n/a | |||||||||
| RefSeq (protein) | n/a | n/a | |||||||||
| Location (UCSC) | n/a | n/a | |||||||||
| PubMed search | n/a | n/a | |||||||||
ARP1 actin-related protein 1 homolog B, centractin beta (yeast), also known as ACTR1B, is a human gene.[1]
This gene encodes a 42.3 kD subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like ACTR1A, is an actin-related protein. These two proteins are of equal length and share 90% amino acid identity. They are present in a constant ratio of approximately 1:15 in the dynactin complex.[1]