Recurrent pyogenic cholangitis: Difference between revisions
No edit summary |
|||
| Line 30: | Line 30: | ||
==Symptoms== | ==Symptoms== | ||
Recurrent pyogenic cholangitis is characterized by recurrent attacks of abdominal pain, fever, and jaundice caused by intrahepatic ductal strictures and calculi. | Recurrent pyogenic cholangitis is characterized by recurrent attacks of [[abdominal pain]], [[fever]], and [[jaundice]] caused by intrahepatic ductal strictures and calculi. | ||
==Diagnostic Findings== | ==Diagnostic Findings== | ||
Revision as of 03:16, 16 March 2009
| Recurrent pyogenic cholangitis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Please Take Over This Page and Apply to be Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [2] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.
Overview
Recurrent pyogenic cholangitis (a.k.a. cholangiohepatitis) is a condition that most commonly affects humans of East Asian origins. It is characterized by recurrent bouts of cholangitis in association with intrahepatic pigment stones and intrahepatic biliary obstruction. [1]
Pathogenesis
In recurrent pyogenic cholangitis the gallstones found within the biliary system are calcium bilirubinate stones or pigmented calcium stones. Calcium bilirubinate stones are prevalent in Asia and very rare in Europe and the United States.
In addition to the presence of these friable concretions of various shapes and sizes within the biliary tree, the bile is often muddy in consistency and contains numerous fine particles of calcium bilirubinate. This differs greatly from cholesterol stones, which are common in Europe and the United States. Pure cholesterol stones contain >96% cholesterol whereas mixed cholesterol stones contain 71.3% cholesterol. The formation of calcium bilirubinate stones in RPC has been attributed to the high incidence of infection with Escherichia coli in the bile. In man, the majority of bilirubin is excreted in the bile as bilirubin glucuronide.
Symptoms
Recurrent pyogenic cholangitis is characterized by recurrent attacks of abdominal pain, fever, and jaundice caused by intrahepatic ductal strictures and calculi.
Diagnostic Findings
- Centrally dilated bile ducts with peripheral tapering.
- Biliary duct stones.
Patient #1: MR images from a patient with recurrent pyogenic cholangitis
Patient #2
References
- ↑ Mi-Suk Park, Jeong-Sik Yu, Ki Whang Kim, Myeong-Jin Kim, Jun Pyo Chung, Sang-Wook Yoon, Jae-Joon Chung, Jong Tae Lee, and Hyung Sik Yoo. Recurrent Pyogenic Cholangitis: Comparison between MR Cholangiography and Direct Cholangiography. Radiology 2001 220: 677-682.
See also