Metirosine

Metirosine

Clinical data
ATC code	C02KB01 (WHO)
Pharmacokinetic data
Elimination half-life	3.4 - 3.7 hours
Identifiers
IUPAC name 2-amino-3-(4-hydroxyphenyl)-2-methyl-propanoic acid
CAS Number	672-87-7
PubChem CID	10123
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C10H13NO3
Molar mass	195.215

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Mechanism of action

Metirosine is an antihypertensive drug. It inhibits the enzyme tyrosine hydroxylase and, therefore, catecholamine synthesis.

Clinical Use

Metirosine is used in the treatment of phaeochromocytoma. It is contra-indicated for the treatment of essential hypertension.