Molsidomine

Chemical structure of molsidomine

Chemical structure of SIN-1

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Overview

Molsidomine is an orally active, long acting vasodilating drug. Molsidomine is metabolized in the liver to the active metabolite SIN-1. SIN-1 is an unstable compound that releases nitric oxide upon decay as the actual vasodilating compound.

Chemistry

Molsidomine as well as SIN-1 are sydnone imines, a class of mesoionic heterocyclic aromatic chemical compounds.

See also

• Nitric oxide
• Nitric oxide releaser
• Vasodilator