Dinoprostone

Dinoprostone

Clinical data
ATC code	G02AD02 (WHO)
Identifiers
IUPAC name 7-[3-hydroxy-2-(3-hydroxyoct-1-enyl)- 5-oxo-cyclopentyl] hept-5-enoic acid
CAS Number	363-24-6
PubChem CID	9691
DrugBank	APRD00927
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C20H32O5
Molar mass	352.465 g/mol

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Overview

In medicine, dinoprostone, is a naturally occurring prostaglandin E2 (PGE2). It has important effects in labour and also stimulates osteoblasts to release factors which stimualtes bone resorption by osteoclasts.

It is sold under the trade name of Cervidil (by Forest Laboratories Inc.), Prostin E₂ (by Pfizer Inc.) and Propess (by Ferring Pharmaceuticals), as a vaginal suppository, to prepare the cervix for labour; it is used to induce labour.

The chemical name is (5Z,11(alpha),13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1-oic acid.

Like other prostaglandins, dinoprostone can be used as an abortifacient.

External links

• Dinoprostone - medlineplus.org
• Cervidil - Forest Laboratories, Inc. (the manufacturer of Cervidil).
• Prostin E2 - pfizer.com
• Cervidil/Prostin E2 - RxList.com
• What is Cervidil? - birthingnaturally.net.
• Cervidil/Prostin E2 - drugs.com