Olopatadine (nasal)

Olopatadine (nasal)

Clinical data
Pregnancy category	C
Routes of administration	Ophthalmic
ATC code	S01GX09 (WHO) R01AC08 (WHO)
Pharmacokinetic data
Elimination half-life	3 hours
Identifiers
IUPAC name {(11Z)-11-[3-(dimethylamino)propylidene]-6,11- dihydrodibenzo[b,e]oxepin-2-yl}acetic acid
CAS Number	113806-05-6
PubChem CID	5281071
DrugBank	APRD00310
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C21H23NO3
Molar mass	337.412 g/mol

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Overview

Olopatadine hydrochloride is an antihistamine and mast cell stabilizer, sold as a prescription eye drop (0.2% solution, trademark Pataday (or Patanol S in some countries), manufactured by Alcon). It is used to treat itching associated with allergic conjunctivitis (eye allergies). Olopatadine hydrochloride 0.1% is sold as trademark Patanol (or Opatanol in some countries).

It should not be used to treat irritation caused by contact lenses. The usual dose for trademark Pataday is 1 drop in each affected eye once a day. The usual dose for trademark Patanol is 1 drop in each affected eye 2 times per day, with 6 to 8 hours between doses.

Its side effects may include headaches (7% of occurrence) burning and stinging (5%), dry eye, foreign body sensation, hyperemia, keratitis, lid edema, pruritus, asthenia, cold syndrome, pharyngitis, rhinitis, sinusitis, and taste change.

External links

• Pataday website
• Olopatadine Ophthalmic via MedlinePlus