Esophageal cancer (patient information)

WikiDoc Resources for Esophageal cancer (patient information)
Articles
Most recent articles on Esophageal cancer (patient information) Most cited articles on Esophageal cancer (patient information) Review articles on Esophageal cancer (patient information) Articles on Esophageal cancer (patient information) in N Eng J Med, Lancet, BMJ
Media
Powerpoint slides on Esophageal cancer (patient information) Images of Esophageal cancer (patient information) Photos of Esophageal cancer (patient information) Podcasts & MP3s on Esophageal cancer (patient information) Videos on Esophageal cancer (patient information)
Evidence Based Medicine
Cochrane Collaboration on Esophageal cancer (patient information) Bandolier on Esophageal cancer (patient information) TRIP on Esophageal cancer (patient information)
Clinical Trials
Ongoing Trials on Esophageal cancer (patient information) at Clinical Trials.gov Trial results on Esophageal cancer (patient information) Clinical Trials on Esophageal cancer (patient information) at Google
Guidelines / Policies / Govt
US National Guidelines Clearinghouse on Esophageal cancer (patient information) NICE Guidance on Esophageal cancer (patient information) NHS PRODIGY Guidance FDA on Esophageal cancer (patient information) CDC on Esophageal cancer (patient information)
Books
Books on Esophageal cancer (patient information)
News
Esophageal cancer (patient information) in the news Be alerted to news on Esophageal cancer (patient information) News trends on Esophageal cancer (patient information)
Commentary
Blogs on Esophageal cancer (patient information)
Definitions
Definitions of Esophageal cancer (patient information)
Patient Resources / Community
Patient resources on Esophageal cancer (patient information) Discussion groups on Esophageal cancer (patient information) Patient Handouts on Esophageal cancer (patient information) Directions to Hospitals Treating Esophageal cancer (patient information) Risk calculators and risk factors for Esophageal cancer (patient information)
Healthcare Provider Resources
Symptoms of Esophageal cancer (patient information) Causes & Risk Factors for Esophageal cancer (patient information) Diagnostic studies for Esophageal cancer (patient information) Treatment of Esophageal cancer (patient information)
Continuing Medical Education (CME)
CME Programs on Esophageal cancer (patient information)
International
Esophageal cancer (patient information) en Espanol Esophageal cancer (patient information) en Francais
Business
Esophageal cancer (patient information) in the Marketplace Patents on Esophageal cancer (patient information)
Experimental / Informatics
List of terms related to Esophageal cancer (patient information)

Editor-in-Chief: Jane Wu

Please Join in Editing This Page and Apply to be an Editor-In-Chief for this topic: There can be one or more than one Editor-In-Chief. You may also apply to be an Associate Editor-In-Chief of one of the subtopics below. Please mail us [1] to indicate your interest in serving either as an Editor-In-Chief of the entire topic or as an Associate Editor-In-Chief for a subtopic. Please be sure to attach your CV and or biographical sketch.

What is Esophageal cancer?

Esophageal cancer is not very common in the United States. The esophagus is a hollow muscular tube, starting in the throat and ending at the stomach, and is used to carry the food you swallow to your stomach to be digested. It is hard to detect esophageal cancer in its early stages. Even if you get symptoms, they may not cause you to be alarmed and seek help from your doctor. However, as the cancer grows, symptoms may include dysphagia, chest pain, weight loss and coughing up blood. Treatments include surgery, radiation, chemotherapy and laser therapy. Esophageal cancer patients also need nutritional support.

How do I know if I have esophageal cancer and what are the symptoms of esophageal cancer?

Early stages of esophageal cancer do not display any recognizable symptoms. As the malignant tumors grows larger, people may notice one or more of the following symptoms:

• Dysphagia: This is the most common symptom of esophageal cancer. It causes problems swallowing, with the feeling like the food is stuck in the throat or chest. At first it is often mild, and then gets worse over time. At last, patients can no longer eat and can only consume water.

• Chest pain or chest burning sensation: Chest pain with swallowing may occur if the tumor is large enough to block the esophagus. Some patients describe a feeling of pressure or burning in the chest.

• Hiccups: This happens because of digestive dysfunction of the esophagus.

• vomiting blood: When a tumor invades a blood vessel, vomiting blood occur. This may be the first symptom in some patients.

• Weight loss: This occurs because swallowing problems prevent patients from eating enough to maintain their weight. Other factors include loss of appetite and increase in metabolism from the cancer.

Infections or other health problems may also cause these symptoms. Only a doctor can tell for sure. A person with any of these symptoms should tell the doctor so that problems can be diagnosed and treated as early as possible.

Who is at risk for esophageal cancer?

Studies have found a number of factors that may affect the risk of esophageal cancer. These risk factors are outlined in the table below:

• Gastroesophageal reflux disease (GERD): In some people, acid can reflex from the stomach into the esophagus. This disease is called Gastroesophageal reflux disease (GERD). Clinicl data show that people with GERD have a 2~16 times risk of getting adenocarcinoma of the esophagus than normal.

• Barrett's esophagus: Barrett's esophagus means the condition the squamous cells that usually line the esophagus is replaced with glandular cells when reflux of stomach acid into the lower esophagus continues for a long time.

• Achalasia: This disease is that the muscle at the lower end of the esophagus does not relax properly. As the result, food has trouble in passing into the stomach and tends to collect in the esophagus and the esophagus above this muscle becomes dilated. People with achalasia have a risk of esophageal cancer that is at least 15 times normal.

• Stomach bacteria: Epidemiological survey demonstrates patients treated to get rid of H. pylori get adenocarcinoma of the esophagus more often than expected.

• Injury to the esophagus: Chemical such as lye may cause a severe chemical burn in the esophagus. The scar tissue can make esophagus very narrow after the injury heals. People with these narrow have a high rate of the squamous cell type of esophageal cancer after several years.

• Workplace exposures: Clinical survey show exposure to chemical fumes such as solvents used for dry cleaning may lead to an increased risk of esophageal cancer.

• Tobacco and alcohol

• Diet: About 15% of esophageal cancer can be linked to a diet poor in fruits and vegetables.

• Obesity

• Gender: Men have a 3-fold higher rate of esophageal cancer than women.

• Age: Most cases occur in those 65 and older.

How to know you have esophageal cancer?

It is hard to diagnose esophageal cancer in its early stages. Other problems can also cause the same symptoms such as stomach discomfort , indigestion swallowing and gastroesophageal reflux disease (GERD). So, if you have those symptoms, you had better go to see your doctor to do some tests. They include lab tests, image tests and endoscopy. Among them, the latter is the main test.

• Upper endoscopy and biopsy: It is the main test used to diagnose esophageal cancer when people have certain risk factors or when signs and symptoms suggest this disease may be present. After you are sedated (made sleepy), an endoscope which is a thin, flexible, lighted tube was passed down your throat. Then the doctor can view the lining of your esophagus and other digestive tracts followed. If abnormal areas are noted, biopsies (tissue samples) can be obtained through the endoscope. The tissue samples will be checked by the pathologists under a microscope to see whether cancer is present or not.

• Barium swallow: This is an x-ray test that a person is given an injection of a medication that will temporarily slow bowel movement, so structures can be more easily seen on the x-rays. For this test, the patient drinks a millkshake-like substance called barium. X-ray method called fluroscopy tracks how the barium moves through your esophagus and other digestive tracts such as stomach, and small intestine. Pictures are taken in a variety of positions.

• Computed tomography (CT) scan: CT scans are often used to diagnose esophageal cancer. It can confirm the location of the cancer and show the organs near the esophagus, as well as lymph nodes and distant organs where the cancer might have spread. These are helpful in staging the cancer and in determining whether surgery is a good treatment option.

• Magnetic resonance imaging (MRI): An MRI uses magnetic fields but which is a different imaging type from computed tomography (CT) to produce detailed images of the body. Like computed tomography (CT), a contrast agent may be injected into a patient’s vein to create a better picture. MRI scan takes longer time than CT scan.

• Positron emission tomography (PET) scan: When doing this test, a small amount of a radioactive medium is injected into your body and absorbed by the organs or tissues. This radioactive substance gives off energy to accept to produce the images. PET can provide more helpful information than CT scan and MRI scan. It is useful to see if the cancer has spread to lymph nodes and also useful for your doctor to locate where the cancer has spread.

When to seek urgent medical care

Call your health care provider if symptoms of esophageal cancer develop. If one emerges the following symptoms, seeking urgent medical care as soon as possible:

• Severe dysphagia: Esophageal cancer causes problems swallowing and at last it may make patients swallow nothing. You need to see the doctor to obtain nutrition support.

• Vomiting a lot of blood: This is the result of cancer invading the vessels of esophageal wall. An bundant of blood loss may lead to shock and death.

Diseases with similar symptoms

Other health problems may also cause similar symptoms. Go to see your doctor to verify your diseases as early as possible. Diseases with similar symptoms are listed in the following:

• Gastroesophageal reflux disease

• Barrett's esophagus

• Esophageal achalasia

• Stomach gastritis, gastric ulcer

• Lung cancer

• Depression

Where to find medical care for esophageal cancer

Directions to Hospitals

Prevention of esophageal cancer

Epidemiology data show the following intervention may help to reduce your risk of esophageal cancer

• Treating esophreflux may be able to prevent Barrett esophagus and esophageal cancer.
• Give up smoking
• Eat a healthy, balanced diet rich in fruits and vegetables

Copyleft Sources

http://www.nlm.nih.gov/medlineplus/esophagealcancer.html

http://www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_is_esophagus_cancer_12.asp?sitearea=