Neurofibroma (patient information): Difference between revisions
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Revision as of 14:46, 13 October 2009
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| Neurofibroma (patient information) | |
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| Histopathologic image of cutanous neurofibroma obtained by biopsy | |
| ICD-O: | 9540-9550 |
| DiseasesDB | 23371 |
| MeSH | D009455 |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Jinhui Wu, MD
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Overview of neurofibroma
Neurofibroma is genetic disorders of the nervous system that result in the growth of noncancerous tumors along nerves. Studies suggested that the cause of neurofibroma is related to gene mutations. There are two main forms of neurofibroma: peripheral neurofibromatosis and central neurofibromatosis.
Peripheral neurofibromatosis is common. Usual signs of peripheral neurofibromatosis includes more tan spots on the skin, freckles, lumps on the skin and a variety of bone defects, such as bowing of the legs below the knee. Biopsy is the best way for diagnosis. In some cases, genetic testing of a blood sample is needed to confirm the diagnosis. For treatment, surgery can curative. However, they often grow back.
Central neurofibromatosis is rare. Severity of symptoms varies greatly. They depend on the nerve infiltrated. Acoustic nerve is the most commonly affected. Nervous system examination, hearing tests, computed tomography (CT) and magnetic resonance imaging (MRI) may help the diagnosis. In some cases, genetic testing is done to help confirm the diagnosis. Treatments of central neurofibromatosis include surgery, radiation therapy, chemotherapy, or a combination of them.
See also
Where to find medical care for neurofibroma?
Directions to Hospitals Treating neurofibroma