Prader-Willi syndrome (patient information)

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What is Prader-Willi syndrome?

Prader-Willi syndrome is a congenital (present from birth) disease that involves obesity, decreased muscle tone, decreased mental capacity, and sex glands that produce little or no hormones.

What are the symptoms of Prader-Willi syndrome?

Symptoms may include:

• Almond-shaped eyes
• Delayed motor development
• Floppy newborn infant
• Insatiable appetite, food craving
• Irregular areas of skin that look like bands, stripes, or lines
• Narrow bifrontal skull
• Rapid weight gain
• Skeletal (limb) abnormalities
• Slow mental development
• Small for gestational age
• Undescended testicles in the male infant
• Very small hands and feet in comparison to body

Affected children have an intense craving for food and will do almost anything to get it. This results in uncontrollable weight gain and morbid obesity. Morbid obesity may lead to lung failure with low blood oxygen levels, right-sided heart failure, and death.

Where to find medical care for Prader-Willi syndrome

Directions to Hospitals Treating Prader-Willi syndrome