Pericarditis laboratory studies: Difference between revisions
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==Inflammatory markers== | ==Inflammatory markers== | ||
The following inflammatory markers are often elevated: | |||
*[[Complete Blood Count|CBC]] | |||
*[[C-reactive protein]] | |||
*Erythrocyte sedimentation rate [[ESR]] | |||
==Markers of Myonecrosis== | |||
The following markers of myonecrosis are elevated: | |||
*[[Creatine Kinase]]: Acute pericarditis is associated with a modest increase in serum [[creatine kinase]] MB (CK-MB)<!-- | |||
--><ref name="spodick">{{cite journal | author= Spodick DH | title= Acute pericarditis: current concepts and practice | journal= JAMA | year=2003 | pages=1150–3 | volume=289 | issue=9 | pmid=12622586 | doi= 10.1001/jama.289.9.1150}}</ref><!-- | --><ref name="spodick">{{cite journal | author= Spodick DH | title= Acute pericarditis: current concepts and practice | journal= JAMA | year=2003 | pages=1150–3 | volume=289 | issue=9 | pmid=12622586 | doi= 10.1001/jama.289.9.1150}}</ref><!-- | ||
--><ref name="karja">{{cite journal | author= Karjalainen J, Heikkila J | title= "Acute pericarditis": myocardial enzyme release as evidence for myocarditis | journal= Am Heart J| year=1986| pages=546–52 | volume=111 | issue=3 | pmid=3953365 | doi= 10.1016/0002-8703(86)90062-1}}</ref> | --><ref name="karja">{{cite journal | author= Karjalainen J, Heikkila J | title= "Acute pericarditis": myocardial enzyme release as evidence for myocarditis | journal= Am Heart J| year=1986| pages=546–52 | volume=111 | issue=3 | pmid=3953365 | doi= 10.1016/0002-8703(86)90062-1}}</ref> | ||
*Cardiac [[troponin]] I (cTnI)<!-- | |||
--><ref name="bonnefoy">{{cite journal | author= Bonnefoy E, Godon P, Kirkorian G, Fatemi M, Chevalier P, Touboul P | title= Serum cardiac troponin I and ST-segment elevation in patients with acute pericarditis | journal= Eur Heart J| year=2000| pages=832–6 | volume=21 | issue=10 | pmid=10781355 | doi= 10.1053/euhj.1999.1907}}</ref><!-- | --><ref name="bonnefoy">{{cite journal | author= Bonnefoy E, Godon P, Kirkorian G, Fatemi M, Chevalier P, Touboul P | title= Serum cardiac troponin I and ST-segment elevation in patients with acute pericarditis | journal= Eur Heart J| year=2000| pages=832–6 | volume=21 | issue=10 | pmid=10781355 | doi= 10.1053/euhj.1999.1907}}</ref><!-- | ||
--><ref name="imazio">{{cite journal | author= Imazio M, Demichelis B, Cecchi E, Belli R, Ghisio A, Bobbio M, Trinchero R | title= Cardiac troponin I in acute pericarditis | journal= J Am Coll Cardiol| year=2003| pages=2144–8 | volume=42 | issue=12 | pmid=14680742 | doi= 10.1016/j.jacc.2003.02.001}}</ref> | --><ref name="imazio">{{cite journal | author= Imazio M, Demichelis B, Cecchi E, Belli R, Ghisio A, Bobbio M, Trinchero R | title= Cardiac troponin I in acute pericarditis | journal= J Am Coll Cardiol| year=2003| pages=2144–8 | volume=42 | issue=12 | pmid=14680742 | doi= 10.1016/j.jacc.2003.02.001}}</ref>. | ||
* [[LDH]]: depends on the extent of myocardial involvement | * [[LDH]]: depends on the extent of myocardial involvement | ||
* [[ | * Serum [[myoglobin]]: normal (but not always, usually rises with increased ST segment deviation | ||
* Gallium-67 scanning may help identify inflammatory and leukemic infiltrations | |||
* | |||
==References== | ==References== | ||
Revision as of 00:58, 25 June 2011
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Inflammatory markers
The following inflammatory markers are often elevated:
- CBC
- C-reactive protein
- Erythrocyte sedimentation rate ESR
Markers of Myonecrosis
The following markers of myonecrosis are elevated:
- Creatine Kinase: Acute pericarditis is associated with a modest increase in serum creatine kinase MB (CK-MB)[1][2]
- Cardiac troponin I (cTnI)[3][4].
- LDH: depends on the extent of myocardial involvement
- Serum myoglobin: normal (but not always, usually rises with increased ST segment deviation
- Gallium-67 scanning may help identify inflammatory and leukemic infiltrations
References
- ↑ Spodick DH (2003). "Acute pericarditis: current concepts and practice". JAMA. 289 (9): 1150–3. doi:10.1001/jama.289.9.1150. PMID 12622586.
- ↑ Karjalainen J, Heikkila J (1986). ""Acute pericarditis": myocardial enzyme release as evidence for myocarditis". Am Heart J. 111 (3): 546–52. doi:10.1016/0002-8703(86)90062-1. PMID 3953365.
- ↑ Bonnefoy E, Godon P, Kirkorian G, Fatemi M, Chevalier P, Touboul P (2000). "Serum cardiac troponin I and ST-segment elevation in patients with acute pericarditis". Eur Heart J. 21 (10): 832–6. doi:10.1053/euhj.1999.1907. PMID 10781355.
- ↑ Imazio M, Demichelis B, Cecchi E, Belli R, Ghisio A, Bobbio M, Trinchero R (2003). "Cardiac troponin I in acute pericarditis". J Am Coll Cardiol. 42 (12): 2144–8. doi:10.1016/j.jacc.2003.02.001. PMID 14680742.