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==Physical Examination <ref> Braunwald Zipes Libby.  Heart disease: A textbook of cardiovascular medicine, 6th Edition chapter 43:W.B. Saunders ;.pp 1533</ref> ==
==Physical Examination <ref> Braunwald Zipes Libby.  Heart disease: A textbook of cardiovascular medicine, 6th Edition chapter 43:W.B. Saunders ;.pp 1533</ref> ==
'''Children'''
'''Small VSD''':
'''Small VSD''':


A systolic thrill may be palpable along the left sternal border and a loud holosystolic murmur (harsher quality than that of MR)localized to the left lower sternal border. In patients with small muscular defects, the murmur may end in mid systole because of systolic contraction of the septal musculature.
* Asymptomatic
* A systolic thrill may be palpable along the left sternal border
* Loud holosystolic murmur (harsher quality than that of MR)localized to the left lower sternal border.  
* In patients with small muscular defects, the murmur may end in mid systole because of systolic contraction of the septal musculature.
 


'''Medium-Sized VSD''':
'''Medium-Sized VSD''':


The rare patient who presents with a medium-sized defect or a moderate left-to-right shunt also may have a third heart sound (S3) and a short early '''middiastolic rumble''' due to increased left-sided volume overload.
* Forceful left ventricular impulse
* Systolic thrill along left sternal border
* Heart sound- split with accentuated pulmonic component , third heart sound (S3)(suggest increased flow across mitral valve)
 
 
'''Murmur'''
 
* Harsh holosystolic murmur at 3rd to 4th  intercostal space to left side of sternum (characteristic VSD murmur)
* Rumbling mid-diastolic murmur at cardiac apex suggesting increase flow across the mitral valve.
* Midsystolic ejection murmur due to increased flow across pulmonary valve.  
 
 


'''Large-Sized VSD with Pulmonary Obstructive Disease''':  
'''Large-Sized VSD with Pulmonary Obstructive Disease''':  


In the first 2 years of age the patients have signs of left sided volume overload. After age 2 old, the patients have signs and symptoms of progressive pulmonary vascular obstructive disease. As a consequence, poor growth and left anterior thorax may bulge outward early. JVD may be elevated due to RV failure.
* In the first 2 years of age the patients have signs of left sided volume overload. After age 2 old, the patients have signs and symptoms of progressive pulmonary vascular obstructive disease. As a consequence, poor growth and left anterior thorax may bulge outward early.  
 
* JVD may be elevated due to RV failure.
In the first two years there is a prominent LV impulse, but with the development of pulmonary hypertension, this LV prominence is diminished and cyanosis is present, worsens with effort and with time.
* In the first two years there is a prominent LV impulse, but with the development of pulmonary hypertension, this LV prominence is diminished and cyanosis is present, worsens with effort and with time.


'''Example of VSD murmur:''' [[Media:VSD murmur.mp3]]
'''Example of VSD murmur:''' [[Media:VSD murmur.mp3]]

Revision as of 15:32, 8 July 2011

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]and Leida Perez, M.D.

Associate Editor-In-Chief: Keri Shafer, M.D. [2], Priyamvada Singh, MBBS



Physical Examination [1]

Children


Small VSD:

  • Asymptomatic
  • A systolic thrill may be palpable along the left sternal border
  • Loud holosystolic murmur (harsher quality than that of MR)localized to the left lower sternal border.
  • In patients with small muscular defects, the murmur may end in mid systole because of systolic contraction of the septal musculature.


Medium-Sized VSD:

  • Forceful left ventricular impulse
  • Systolic thrill along left sternal border
  • Heart sound- split with accentuated pulmonic component , third heart sound (S3)(suggest increased flow across mitral valve)


Murmur

  • Harsh holosystolic murmur at 3rd to 4th intercostal space to left side of sternum (characteristic VSD murmur)
  • Rumbling mid-diastolic murmur at cardiac apex suggesting increase flow across the mitral valve.
  • Midsystolic ejection murmur due to increased flow across pulmonary valve.


Large-Sized VSD with Pulmonary Obstructive Disease:

  • In the first 2 years of age the patients have signs of left sided volume overload. After age 2 old, the patients have signs and symptoms of progressive pulmonary vascular obstructive disease. As a consequence, poor growth and left anterior thorax may bulge outward early.
  • JVD may be elevated due to RV failure.
  • In the first two years there is a prominent LV impulse, but with the development of pulmonary hypertension, this LV prominence is diminished and cyanosis is present, worsens with effort and with time.

Example of VSD murmur: Media:VSD murmur.mp3

References

  1. Braunwald Zipes Libby. Heart disease: A textbook of cardiovascular medicine, 6th Edition chapter 43:W.B. Saunders ;.pp 1533

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