Atrioventricular septal defect epidemiology and demographics: Difference between revisions
New page: {{Template:Atrioventricular septal defect}} {{CMG}} ==Epidemiology and demographics== In the US, the prevalence of atrioventricular septal defects is between 3-5% in live births or about ... |
|||
| Line 3: | Line 3: | ||
==Epidemiology and demographics== | ==Epidemiology and demographics== | ||
In the US, the prevalence of atrioventricular septal defects is between 3-5% in live births or about 0.19 per 1000 live births. The incidence of AVSD is higher in stillborn births, at a rate of approximately 7%. One explanation for this increase is this population's propensity for chromosal and other anomalies. Of live births, approximately 45% of infants with Down syndrome and congenital heart disease have an atrioventricular canal | In the US, the prevalence of atrioventricular septal defects is between 3-5% in live births or about 0.19 per 1000 live births. The incidence of AVSD is higher in stillborn births, at a rate of approximately 7%. One explanation for this increase is this population's propensity for chromosal and other anomalies. Of live births, approximately 45% of infants with Down syndrome and congenital heart disease have an atrioventricular canal defect. Atrioventricular septal defects are distributed about equal between males and females.<ref name="pmid2063835">{{cite journal| author=Rosenthal GL, Wilson PD, Permutt T, Boughman JA, Ferencz C| title=Birth weight and cardiovascular malformations: a population-based study. The Baltimore-Washington Infant Study. | journal=Am J Epidemiol | year= 1991 | volume= 133 | issue= 12 | pages= 1273-81 | pmid=2063835 | doi= | pmc= | url= }} </ref> | ||
There is some evidence to suggest a potential link between atrioventricular septal defects and familial clustering. Approximately 14% of women with a common atrioventricular canal pass on the congenital heart disease to their children. In one analysis, 11.7% of children with atrioventricular septal defects had a family history of congenital heart disease<ref name="pmid8249947">{{cite journal| author=Digilio MC, Marino B, Cicini MP, Giannotti A, Formigari R, Dallapiccola B| title=Risk of congenital heart defects in relatives of patients with atrioventricular canal. | journal=Am J Dis Child | year= 1993 | volume= 147 | issue= 12 | pages= 1295-7 | pmid=8249947 | doi= | pmc= | url= }} </ref> | There is some evidence to suggest a potential link between atrioventricular septal defects and familial clustering. Approximately 14% of women with a common atrioventricular canal pass on the congenital heart disease to their children. In one analysis, 11.7% of children with atrioventricular septal defects had a family history of congenital heart disease<ref name="pmid8249947">{{cite journal| author=Digilio MC, Marino B, Cicini MP, Giannotti A, Formigari R, Dallapiccola B| title=Risk of congenital heart defects in relatives of patients with atrioventricular canal. | journal=Am J Dis Child | year= 1993 | volume= 147 | issue= 12 | pages= 1295-7 | pmid=8249947 | doi= | pmc= | url= }} </ref> | ||
Revision as of 13:18, 12 July 2011
|
Atrioventricular septal defect Microchapters |
|
Differentiating Atrioventricular septal defect from other Diseases |
|---|
|
Diagnosis |
|
Treatment |
|
Atrioventricular septal defect epidemiology and demographics On the Web |
|
American Roentgen Ray Society Images of Atrioventricular septal defect epidemiology and demographics |
|
FDA on Atrioventricular septal defect epidemiology and demographics |
|
CDC on Atrioventricular septal defect epidemiology and demographics |
|
Atrioventricular septal defect epidemiology and demographics in the news |
|
Blogs on Atrioventricular septal defect epidemiology and demographics |
|
Risk calculators and risk factors for Atrioventricular septal defect epidemiology and demographics |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Epidemiology and demographics
In the US, the prevalence of atrioventricular septal defects is between 3-5% in live births or about 0.19 per 1000 live births. The incidence of AVSD is higher in stillborn births, at a rate of approximately 7%. One explanation for this increase is this population's propensity for chromosal and other anomalies. Of live births, approximately 45% of infants with Down syndrome and congenital heart disease have an atrioventricular canal defect. Atrioventricular septal defects are distributed about equal between males and females.[1]
There is some evidence to suggest a potential link between atrioventricular septal defects and familial clustering. Approximately 14% of women with a common atrioventricular canal pass on the congenital heart disease to their children. In one analysis, 11.7% of children with atrioventricular septal defects had a family history of congenital heart disease[2]
There is no epidemiological evidence to support any variation of incidence and prevalence based on race, sex or age. Onset is generally early in life, occurring within the first 6 weeks of life. In rare cases, patients can be asymptomatic during development and may experience a latent onset as cyanosis develops into a severe complication.
References
- ↑ Rosenthal GL, Wilson PD, Permutt T, Boughman JA, Ferencz C (1991). "Birth weight and cardiovascular malformations: a population-based study. The Baltimore-Washington Infant Study". Am J Epidemiol. 133 (12): 1273–81. PMID 2063835.
- ↑ Digilio MC, Marino B, Cicini MP, Giannotti A, Formigari R, Dallapiccola B (1993). "Risk of congenital heart defects in relatives of patients with atrioventricular canal". Am J Dis Child. 147 (12): 1295–7. PMID 8249947.