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| Line 1: |
Line 1: |
| ==Major Interactions==
| | __NOTOC__ |
| {{refbegin|3}} | | {{Tenecteplase}} |
| * [[abciximab]]
| | {{CMG}}; {{AE}} {{SS}} |
| * [[Acova]]
| |
| * [[Aggrastat]]
| |
| * [[Angiomax]]
| |
| * [[anisindione]]
| |
| * [[Aptivus]]
| |
| * [[ardeparin]]
| |
| * [[argatroban]]
| |
| * [[Arixtra]]
| |
| * [[Arixtra 10 mg/dose]]
| |
| * [[Arixtra 5 mg/dose]]
| |
| * [[Arixtra 7.5 mg/dose]]
| |
| * [[Bexxar Dosimetric]]
| |
| * [[Bexxar I 131 Dosimetric]]
| |
| * [[Bexxar I 131 Therapeutic]]
| |
| * [[BexxarTherapeutic]]
| |
| * [[bivalirudin]]
| |
| * [[Clexane]]
| |
| * [[Clexane Forte]]
| |
| * [[Coumadin]]
| |
| * [[dalteparin]]
| |
| * [[danaparoid]]
| |
| * [[dasatinib]]
| |
| * [[desirudin]]
| |
| * [[dicumarol]]
| |
| * [[drotrecogin]]
| |
| * [[drotrecogin alfa]]
| |
| * [[enoxaparin]]
| |
| * [[eptifibatide]]
| |
| * [[fondaparinux]]
| |
| * [[Fragmin]]
| |
| * [[Hep-Lock]]
| |
| * [[Hep-Pak]]
| |
| * [[Hep-Pak CVC]]
| |
| * [[heparin]]
| |
| * [[Heparin Lock Flush]]
| |
| * [[ibritumomab]]
| |
| * [[In-111 Zevalin]]
| |
| * [[Innohep]]
| |
| * [[Integrilin]]
| |
| * [[iodine I 131 tositumomab]]
| |
| * [[Iprivask]]
| |
| * [[Jantoven]]
| |
| * [[lepirudin]]
| |
| * [[Lovenox]]
| |
| * [[Lovenox HP]]
| |
| * [[Miradon]]
| |
| * [[Normiflo]]
| |
| * [[Orgaran]]
| |
| * [[Refludan]]
| |
| * [[Reopro]]
| |
| * [[Sprycel]]
| |
| * [[tinzaparin]]
| |
| * [[tipranavir]]
| |
| * [[tirofiban]]
| |
| * [[tositumomab]]
| |
| * [[warfarin]]
| |
| * [[Xigris]]
| |
| * [[Y-90 Zevalin]]
| |
| {{refend}}
| |
| | |
| ==Moderate Interactions==
| |
| {{refbegin|3}}
| |
| * [[Acetylsalicylic Acid]]
| |
| * [[Actron]]
| |
| * [[Acular]]
| |
| * [[Acular LS]]
| |
| * [[Acular PF]]
| |
| * [[Acuprin 81]]
| |
| * [[Advil]]
| |
| * [[Advil Childrens]]
| |
| * [[Advil Junior Strength]]
| |
| * [[Advil Liquigel]]
| |
| * [[Advil Migraine]]
| |
| * [[Advil Pediatric]]
| |
| * [[Aflaxen]]
| |
| * [[Aleve]]
| |
| * [[Aleve Caplet]]
| |
| * [[Aleve Easy Open Arthritis]]
| |
| * [[Aleve Gelcap]]
| |
| * [[Amigesic]]
| |
| * [[Anaflex]]
| |
| * [[Anafranil]]
| |
| * [[Anaprox]]
| |
| * [[Anaprox-DS]]
| |
| * [[Ansaid]]
| |
| * [[Argesic-SA]]
| |
| * [[Arthritis Pain]]
| |
| * [[Arthropan]]
| |
| * [[ASA]]
| |
| * [[Ascriptin Enteric]]
| |
| * [[Aspergum Cherry]]
| |
| * [[Aspergum Orginal]]
| |
| * [[Aspir-Low]]
| |
| * [[aspirin]]
| |
| * [[aspirin extended release]]
| |
| * [[Aspirin Lite Coat]]
| |
| * [[Aspirin Litecoat]]
| |
| * [[Aspirin Low Strength]]
| |
| * [[Aspirtab]]
| |
| * [[Bayer Aspirin]]
| |
| * [[Bayer Aspirin Regimen]]
| |
| * [[Bayer Aspirin Sugar Free]]
| |
| * [[Bayer Aspirin with Calcium]]
| |
| * [[Bayer Childrens Aspirin]]
| |
| * [[Bayer Low Strength]]
| |
| * [[Bayer Plus]]
| |
| * [[Bayer Select Backache Pain Formula]]
| |
| * [[Bismarex]]
| |
| * [[Bismatrol]]
| |
| * [[Bismatrol Maximum Strength]]
| |
| * [[bismuth subsalicylate]]
| |
| * [[bromfenac]]
| |
| * [[bromfenac ophthalmic]]
| |
| * [[Buffered Aspirin]]
| |
| * [[Bufferin]]
| |
| * [[Bufferin Arthritis Strength]]
| |
| * [[Bufferin Extra Strength]]
| |
| * [[Buffex]]
| |
| * [[Cataflam]]
| |
| * [[Celexa]]
| |
| * [[Ceprotin]]
| |
| * [[Childrens Ibuprofen Berry]]
| |
| * [[Childrens Kaopectate]]
| |
| * [[choline salicylate]]
| |
| * [[citalopram]]
| |
| * [[Clinoril]]
| |
| * [[clomipramine]]
| |
| * [[clopidogrel]]
| |
| * [[Cymbalta]]
| |
| * [[Daypro]]
| |
| * [[desvenlafaxine]]
| |
| * [[dexfenfluramine]]
| |
| * [[diclofenac]]
| |
| * [[diclofenac ophthalmic]]
| |
| * [[diclofenac potassium]]
| |
| * [[diclofenac sodium]]
| |
| * [[diclofenac sodium extended release]]
| |
| * [[diclofenac topical]]
| |
| * [[diflunisal]]
| |
| * [[dipyridamole]]
| |
| * [[Disalcid]]
| |
| * [[Doans Pills]]
| |
| * [[Doans Pills Extra Strength]]
| |
| * [[Dolobid]]
| |
| * [[dong quai]]
| |
| * [[duloxetine]]
| |
| * [[DurAct]]
| |
| * [[Easprin]]
| |
| * [[EC-Naprosyn]]
| |
| * [[Ecotrin]]
| |
| * [[Ecotrin Adult Low Strength]]
| |
| * [[Ecotrin Maximum Strength]]
| |
| * [[Effexor]]
| |
| * [[Effexor XR]]
| |
| * [[Elmiron]]
| |
| * [[Empirin]]
| |
| * [[Entaprin]]
| |
| * [[Entercote]]
| |
| * [[epoprostenol]]
| |
| * [[escitalopram]]
| |
| * [[etodolac]]
| |
| * [[etodolac extended release]]
| |
| * [[Extra Strength Bayer]]
| |
| * [[Fasprin]]
| |
| * [[Feldene]]
| |
| * [[fenfluramine]]
| |
| * [[fenoprofen]]
| |
| * [[Flector Patch]]
| |
| * [[Flolan]]
| |
| * [[fluoxetine]]
| |
| * [[fluoxetine extended release]]
| |
| * [[flurbiprofen]]
| |
| * [[flurbiprofen ophthalmic]]
| |
| * [[fluvoxamine]]
| |
| * [[fluvoxamine extended release]]
| |
| * [[garlic]]
| |
| * [[Garlic Oil]]
| |
| * [[Genacote]]
| |
| * [[Gennin-FC]]
| |
| * [[Genpril]]
| |
| * [[Genprin]]
| |
| * [[ginger]]
| |
| * [[Ginger Root]]
| |
| * [[Ginger (obs)]]
| |
| * [[gingko]]
| |
| * [[gingko biloba]]
| |
| * [[ginkgo]]
| |
| * [[ginseng]]
| |
| * [[Halfprin]]
| |
| * [[Haltran]]
| |
| * [[hemin]]
| |
| * [[Hofels Ginger One A Day]]
| |
| * [[Ibu]]
| |
| * [[IBU-200]]
| |
| * [[Ibu-4]]
| |
| * [[Ibu-6]]
| |
| * [[Ibu-8]]
| |
| * [[Ibu-Tab]]
| |
| * [[ibuprofen]]
| |
| * [[Ibuprofen PMR]]
| |
| * [[iloprost]]
| |
| * [[Indocin]]
| |
| * [[Indocin SR]]
| |
| * [[indomethacin]]
| |
| * [[indomethacin extended release]]
| |
| * [[K-Pek]]
| |
| * [[Kao-Tin Bismuth Subsalicylate Formula]]
| |
| * [[Kaopectate]]
| |
| * [[Kaopectate Anti-Diarrheal Upset Stomach Reliever]]
| |
| * [[Kaopectate Extra Strength]]
| |
| * [[Kapectolin (New Formula)]]
| |
| * [[ketoprofen]]
| |
| * [[ketoprofen extended release]]
| |
| * [[ketorolac]]
| |
| * [[ketorolac ophthalmic]]
| |
| * [[Leader Naproxen Sodium]]
| |
| * [[Lexapro]]
| |
| * [[Litecoat Aspirin]]
| |
| * [[Lodine]]
| |
| * [[Lodine XL]]
| |
| * [[Low Dose ASA]]
| |
| * [[Luvox]]
| |
| * [[Luvox CR]]
| |
| * [[Maalox Total Stomach Relief]]
| |
| * [[Magan]]
| |
| * [[magnesium salicylate]]
| |
| * [[Marthritic]]
| |
| * [[Maximum Strength Stress]]
| |
| * [[meclofenamate]]
| |
| * [[Meclomen]]
| |
| * [[mefenamic acid]]
| |
| * [[meloxicam]]
| |
| * [[Menadol]]
| |
| * [[Meridia]]
| |
| * [[Midol Extended Relief]]
| |
| * [[Midol IB]]
| |
| * [[Midol Maximum Strength Cramp Formula]]
| |
| * [[Minitabs]]
| |
| * [[Mobic]]
| |
| * [[Mobidin]]
| |
| * [[Mono-Gesic]]
| |
| * [[Motrin]]
| |
| * [[Motrin Childrens]]
| |
| * [[Motrin IB]]
| |
| * [[Motrin Infant Drops]]
| |
| * [[Motrin Junior Strength]]
| |
| * [[Motrin Migraine Pain]]
| |
| * [[MST]]
| |
| * [[nabumetone]]
| |
| * [[Nalfon]]
| |
| * [[Naprelan '375']]
| |
| * [[Naprelan '500']]
| |
| * [[Naprosyn]]
| |
| * [[naproxen]]
| |
| * [[naproxen sodium]]
| |
| * [[Naproxen Sodium DS]]
| |
| * [[naproxen sodium extended release]]
| |
| * [[NeoProfen]]
| |
| * [[nepafenac ophthalmic]]
| |
| * [[Nevanac]]
| |
| * [[Norwich Aspirin]]
| |
| * [[Nuprin]]
| |
| * [[Nuprin Backache Caplet]]
| |
| * [[Ocufen]]
| |
| * [[Orudis]]
| |
| * [[Orudis KT]]
| |
| * [[Oruvail]]
| |
| * [[oxaprozin]]
| |
| * [[Panhematin]]
| |
| * [[paroxetine]]
| |
| * [[paroxetine extended release]]
| |
| * [[paroxetine mesylate]]
| |
| * [[Paxil]]
| |
| * [[Paxil CR]]
| |
| * [[Pediacare Fever]]
| |
| * [[pentosan polysulfate sodium]]
| |
| * [[Peptic Relief]]
| |
| * [[Pepto-Bismol]]
| |
| * [[Pepto-Bismol Maximum Strength]]
| |
| * [[Persantine]]
| |
| * [[Persantine IV]]
| |
| * [[Pexeva]]
| |
| * [[phenyl salicylate]]
| |
| * [[phenylbutazone]]
| |
| * [[Pink Bismuth]]
| |
| * [[piroxicam]]
| |
| * [[Plavix]]
| |
| * [[Pondimin]]
| |
| * [[Ponstel]]
| |
| * [[Pristiq]]
| |
| * [[prostacyclin]]
| |
| * [[protein C]]
| |
| * [[Protexel]]
| |
| * [[Prozac]]
| |
| * [[Prozac Weekly]]
| |
| * [[Q-Profen]]
| |
| * [[Rapiflux]]
| |
| * [[Redux]]
| |
| * [[Relafen]]
| |
| * [[Remodulin]]
| |
| * [[Rexolate]]
| |
| * [[Rufen]]
| |
| * [[Saleto-200]]
| |
| * [[Saleto-400]]
| |
| * [[Saleto-600]]
| |
| * [[Saleto-800]]
| |
| * [[Salflex]]
| |
| * [[salsalate]]
| |
| * [[Salsitab]]
| |
| * [[Sarafem]]
| |
| * [[Selfemra]]
| |
| * [[sertraline]]
| |
| * [[sibutramine]]
| |
| * [[Sloprin]]
| |
| * [[sodium salicylate]]
| |
| * [[sodium thiosalicylate]]
| |
| * [[Solaraze]]
| |
| * [[St. Joseph Aspirin]]
| |
| * [[St. Joseph Aspirin Adult Chewable]]
| |
| * [[St. Joseph Aspirin Adult EC]]
| |
| * [[Stanback Analgesic]]
| |
| * [[Stress Maximum Strength]]
| |
| * [[sulindac]]
| |
| * [[suprofen ophthalmic]]
| |
| * [[Therapy Bayer]]
| |
| * [[Ticlid]]
| |
| * [[ticlopidine]]
| |
| * [[Tolectin]]
| |
| * [[Tolectin 600]]
| |
| * [[Tolectin DS]]
| |
| * [[tolmetin]]
| |
| * [[Toradol]]
| |
| * [[Toradol IM]]
| |
| * [[Toradol IV/IM]]
| |
| * [[treprostinil]]
| |
| * [[Tri-Buffered Aspirin]]
| |
| * [[Tusal]]
| |
| * [[venlafaxine]]
| |
| * [[venlafaxine extended release]]
| |
| * [[Ventavis]]
| |
| * [[Voltaren]]
| |
| * [[Voltaren Ophthalmic]]
| |
| * [[Voltaren Topical]]
| |
| * [[Voltaren-XR]]
| |
| * [[Xibrom]]
| |
| * [[YSP Aspirin]]
| |
| * [[Zero-Order Release]]
| |
| * [[zingiber]]
| |
| * [[Zoloft]]
| |
| * [[Zorprin]]
| |
| {{refend}} | |
| | |
| ==Minor Interactions==
| |
| | |
| {{refbegin|3}} | |
| * [[capsaicin]]
| |
| * [[capsicum]]
| |
| * [[chamomile]]
| |
| * [[clove]]
| |
| * [[fenugreek]]
| |
| * [[feverfew]]
| |
| * [[matricaria]]
| |
| * [[turmeric]]
| |
| {{refend}} | |
| | |
| | |
| | |
| | |
| {{FDA}}
| |
| | |
|
| |
|
| | ==Drug Interactions== |
|
| |
|
| | Formal interaction studies of TNKase with other drugs have not been performed. Patients studied in clinical trials of TNKase were routinely treated with [[heparin]] and [[aspirin]]. Anticoagulants (such as [[heparin]] and vitamin K antagonists) and drugs that alter platelet function (such as [[acetylsalicylic acid]], [[dipyridamole]], and GP IIb/IIIa inhibitors) may increase the risk of bleeding if administered prior to, during, or after TNKase therapy.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = TNKASE (TENECTEPLASE) KIT [GENENTECH, INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=69e391bf-1250-4083-aa60-6aa41c33657f | publisher = | date = | accessdate = 6 February 2014 }}</ref> |
| | ==References== |
|
| |
|
| | {{Reflist|2}} |
|
| |
|
| | [[Category:Thrombolytic drugs]] |
| | [[Category:Cardiovascular Drugs]] |
| [[Category:Drugs]] | | [[Category:Drugs]] |
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