Dextro-transposition of the great arteries differential diagnosis

Patients with tricuspid atresia should be differentiated from other cardiac and non-cardiac causes of cyanosis-

Cardiac causes (starts with 't')-

• Tetralogy of Fallot
• Truncus arteriosus
• Total anomalous pulmonary venous connection
• Other tricuspid valve abnormalities like tricuspid regurgitaton, tricuspid stenosis

Other less common causes are- pulmonary atresia, hypoplastic left heart syndrome, anomalous systemic venous connection.

Non-cardiac causes

• Pulmonary diseases - Structural abnormalities of the lung, V/P (ventilation-perfusion mismatch), airway obstruction, pneumothorax, and hypoventilation.
• Abnormal hemoglobin like methemoglobin, polycythemia
• Peripheral cyanosis for e.g. sepsis, hypoglycemia, dehydration, and hypoadrenalism.