Schwannoma: Difference between revisions
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Schwannomas can arise from a genetic disorder called [[schwannomatosis]]. | Schwannomas can arise from a genetic disorder called [[schwannomatosis]]. | ||
A '''schwannoma''' (also known as an "acoustic neuroma,"<ref name="Bolognia" /> "neurilemmoma,"<ref name="Andrews">James, William; Berger, Timothy; Elston, Dirk (2005). ''Andrews' Diseases of the Skin: Clinical Dermatology''. (10th ed.). Saunders. ISBN 0-7216-2921-0.</ref>{{rp|621}} "neurinoma,"<ref name="Bolognia" /> "neurolemmoma,"<ref name="Bolognia" /> and "Schwann cell tumor"<ref name="Bolognia">{{cite book |author=Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |pages= |isbn=1-4160-2999-0 |oclc= |doi= |accessdate=}}</ref>) is a benign [[nerve sheath tumor]] composed of [[Schwann cell]]s, which normally produce the insulating [[myelin sheath]] covering [[Peripheral nervous system|peripheral nerves]]. | |||
Schwannomas are very homogeneous tumors, consisting only of Schwann cells. The tumor cells always stay on the outside of the nerve, but the tumor itself may either push the nerve aside and/or up against a bony structure (thereby possibly causing damage). Schwannomas are relatively slow growing. For reasons not yet understood, schwannomas are mostly [[benign]] and less than 1% become malignant, degenerating into a form of [[cancer]] known as [[neurofibrosarcoma]]. | |||
Schwannomas can arise from a genetic disorder called [[neurofibromatosis]]. They are universally [[S-100 protein|S-100]] positive. | |||
Schwannomas can be removed surgically, but can then recur. | |||
==Additional images== | |||
<gallery> | |||
Image:Peripheral schwannoma Antoni type A (2).JPG | |||
Image:Subcutaneous schwannoma (1) Antoni B.jpg|Subcutaneous schwannoma | |||
Image:Subcutaneous schwannoma (2) Antoni B.jpg | |||
Image:Subcutaneous schwannoma (3) Antoni B.jpg | |||
Image:Subcutaneous schwannoma (4) S-100 immunostain.jpg | |||
</gallery> | |||
== References == | |||
<references/> | |||
==See also== | |||
*[[Neurofibroma]] | |||
*[[Vestibular schwannoma]] (Acoustic neuroma) | |||
{{Nervous tissue tumors}} | |||
[[Category:PNS neoplasia]] | |||
[[Category:Dermal and subcutaneous growths]] | |||
[[Category:Oncology]] | |||
[[Category:Dermatology]] | |||
[[Category:Neurology]] | |||
[[cs:Neurinom]] | |||
[[de:Schwannom]] | |||
[[es:Schwannoma]] | |||
[[fa:شوانوما]] | |||
[[it:Schwannoma]] | |||
[[pl:Nerwiakowłókniak]] | |||
==See also== | ==See also== | ||
Revision as of 22:02, 28 July 2011
For patient information click here
| Schwannoma | |
| ICD-O: | 9560/0 |
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| DiseasesDB | 33713 |
| MeSH | D009442 |
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Synonyms and keywords: Acoustic neuroma, acoustic neurinoma, or acoustic neurilemoma
Overview
A schwannoma is a kind of tumor originating from the Schwann cells. The insulating myelin sheath which covers peripheral nerves is produced by the Schwann cells. Hence, one kind of tumor originating from the Schwann cells is called a schwannoma.
Schwannomas are very homogenous tumors consisting only of Schwann cells. The tumor cells always stay on the outside of the nerve, but the tumor itself may either push the nerve aside and/or up against a bony structure (thereby possibly causing damage). Schwannomas are relatively slow growing. For reasons not yet understood, schwannomas are mostly benign and less than 1% become malignant (degenerate into cancer).
Schwannomas can arise from a genetic disorder called schwannomatosis.
A schwannoma (also known as an "acoustic neuroma,"[1] "neurilemmoma,"[2]:621 "neurinoma,"[1] "neurolemmoma,"[1] and "Schwann cell tumor"[1]) is a benign nerve sheath tumor composed of Schwann cells, which normally produce the insulating myelin sheath covering peripheral nerves.
Schwannomas are very homogeneous tumors, consisting only of Schwann cells. The tumor cells always stay on the outside of the nerve, but the tumor itself may either push the nerve aside and/or up against a bony structure (thereby possibly causing damage). Schwannomas are relatively slow growing. For reasons not yet understood, schwannomas are mostly benign and less than 1% become malignant, degenerating into a form of cancer known as neurofibrosarcoma.
Schwannomas can arise from a genetic disorder called neurofibromatosis. They are universally S-100 positive.
Schwannomas can be removed surgically, but can then recur.
Additional images
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Subcutaneous schwannoma
.JPG){kind=link}
_Antoni_B.jpg){kind=link}
_Antoni_B.jpg){kind=link}
_Antoni_B.jpg){kind=link}
_S-100_immunostain.jpg){kind=link}
References
See also
- Neurofibroma
- Vestibular schwannoma (Acoustic neuroma)
Template:Nervous tissue tumors
cs:Neurinom de:Schwannom fa:شوانوما it:Schwannoma