Atrial septal defect risk factors: Difference between revisions
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Factors in the mother that may increase the risk of this condition include: | Factors in the mother that may increase the risk of this condition include: | ||
*Age over 40 | *Age over 40 | ||
*Alcoholism | *Alcoholism <ref name="pmid1397217">{{cite journal| author=Tikkanen J, Heinonen OP| title=Risk factors for atrial septal defect. | journal=Eur J Epidemiol | year= 1992 | volume= 8 | issue= 4 | pages= 509-15 | pmid=1397217 | doi= | pmc= | url= }} </ref>. | ||
*Diabetes | *Diabetes | ||
*Prenatal nutrition | *Prenatal nutrition |
Revision as of 02:57, 18 August 2011
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, MBBS [[2]]; Cafer Zorkun, M.D., Ph.D. [3]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [[4]]
Overview
The cause of atrial septal defects is not known. There does appear to be a genetic component to the disease as it often occurs in patients with Down syndrome. As a parent, if you or a sibling of a child have a congenital heart defect, then you should consider genetic counseling.
Risk factors
- Generally, TGA is not known to be associated with any specific single gene defect, but some studies have shown possible genetic association in some cases of TGA, involving deletions of chromosome 22q11.
Factors in the mother that may increase the risk of this condition include:
- Age over 40
- Alcoholism [1].
- Diabetes
- Prenatal nutrition
- Rubella or other viral illness during pregnancy