Deep vein thrombosis screening: Difference between revisions
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==Who should be screened?== | ==Who should be screened?== | ||
Patients having any of the following, should be screened for inherited [[Thrombophilia]] | |||
*Initial thrombosis occurring at age<50, without an immediately identified risk factor | |||
*Positive family history of thromboembolism at age<50 | |||
*Recurrent venous thrombosis | |||
*Thrombosis occurring in unusual vascular beds such as portal, hepatic, mesenteric, or cerebral veins | |||
*History of [[warfarin]]-induced skin necrosis. | |||
Revision as of 18:58, 25 August 2011
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Overview:Value of screening
In-spite of identifying patients at increased risk of VTE, there is no clear clinical value for screening, the following reason explains
- The strongest risk factor for VTE recurrence is the prior VTE event itself.
- After discontinuation of warfarin in VTE patients, especially where the cause was unknown, there are still at high risk of recurrence. irrespective of the presence of inherited thrombophilia.
- Anticoagulant prophylaxis is rarely recommended in asymptomatic affected family members outside of high risk situations.
Who should be screened?
Patients having any of the following, should be screened for inherited Thrombophilia
- Initial thrombosis occurring at age<50, without an immediately identified risk factor
- Positive family history of thromboembolism at age<50
- Recurrent venous thrombosis
- Thrombosis occurring in unusual vascular beds such as portal, hepatic, mesenteric, or cerebral veins
- History of warfarin-induced skin necrosis.